Evidence map›Paper›PMID 40044856›Full record

ArticleNature2025

Fine-scale patterns of SARS-CoV-2 spread from identical pathogen sequences.

Cécile Tran-Kiem, Miguel I Paredes, Amanda C Perofsky, Lauren A Frisbie, Hong Xie, Kevin Kong, Amelia Weixler, Alexander L Greninger, Pavitra Roychoudhury, JohnAric M Peterson and 16 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Rapid evolution reveals long-range spread of SARS-CoV-2.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Reconstructing the early spatial spread of pandemic respiratory viruses in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Uncovering heterogeneous intercommunity disease transmission from neutral allele frequency time series.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors.

Cécile Tran-KiemVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. ctrankie@fredhutch.org.ORCID 0000-0003-0563-8428
Miguel I ParedesVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Amanda C PerofskyBrotman Baty Institute, University of Washington, Seattle, WA, USA.ORCID 0000-0001-7341-9193
Lauren A FrisbieWashington State Department of Health, Shoreline, WA, USA.
Hong XieDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Kevin KongDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Amelia WeixlerDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Alexander L GreningerVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID 0000-0002-7443-0527
Pavitra RoychoudhuryVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID 0000-0002-4567-8232
JohnAric M PetersonWashington State Department of Health, Shoreline, WA, USA.
Andrew DelgadoWashington State Department of Health, Shoreline, WA, USA.
Holly HalsteadWashington State Department of Health, Shoreline, WA, USA.
Drew MacKellarWashington State Department of Health, Shoreline, WA, USA.
Philip DykemaWashington State Department of Health, Shoreline, WA, USA.
Luis GamboaBrotman Baty Institute, University of Washington, Seattle, WA, USA.
Chris D FrazarDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Erica RykeDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Jeremy StoneBrotman Baty Institute, University of Washington, Seattle, WA, USA.
David ReinhartBrotman Baty Institute, University of Washington, Seattle, WA, USA.
Lea StaritaBrotman Baty Institute, University of Washington, Seattle, WA, USA.
Allison ThibodeauWashington State Department of Health, Shoreline, WA, USA.
Cory YunWashington State Department of Health, Shoreline, WA, USA.
Frank AragonaWashington State Department of Health, Shoreline, WA, USA.
Allison BlackWashington State Department of Health, Shoreline, WA, USA.
Cécile ViboudFogarty International Center, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-3243-4711
Trevor BedfordVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.

Funding

University of Washington Medical Scientist Training ProgramT32GM153182 · NIGMS · UNIVERSITY OF WASHINGTON · PI MARSHALL S. HORWITZ · 2024 to 2026
$5.3M
Real-time tracking of virus evolution for vaccine strain selection and epidemiological investigationR35GM119774 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BEDFORD, TREVOR BC · 2016 to 2025
$4.1M
High-Performance Compute Cluster for Comprehensive Cancer and Infectious Diseases ResearchS10OD028685 · OD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BRADLEY, PHILIP · 2020 to 2020
$2.0M
FHCRC High-Performance Computing ClusterS10OD020069 · OD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KOOPERBERG, CHARLES L · 2015 to 2015
$600k
NCEZID CDC HHS U01 CK000630NIGMS NIH HHS R35 GM119774NIGMS NIH HHS T32 GM153182NIH HHS S10 OD020069NIH HHS S10 OD028685
6 · The paper itself

Abstract

Pathogen genomics can provide insights into underlying infectious disease transmission patterns

Indexed as

COVID-19Genome, ViralSARS-CoV-2AdolescentAdultAgedAge FactorsChildChild, PreschoolFemaleGenomicsHumansInfantMaleMiddle AgedWashington

Identifiers

PMID40044856
PMCPMC11964829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.