ArticleNature2025
Clonal dynamics and somatic evolution of haematopoiesis in mouse.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.
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31citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed.
- Mechanisms of Hematopoietic Stem Cell Aging and Emerging Rejuvenation Strategies.Stem cell reviews and reports · 2026Review
- Somatic mutations and single-nucleus transcriptomics reveal uniquely human properties of neuronal aging.bioRxiv : the preprint server for biology · 2026Article
- Neonatal critical illness is associated with pancytopenia development in childhood.medRxiv : the preprint server for health sciences · 2026Article
- Activating an interleukin 4-FLT3-STAT6 axis in multipotent progenitors restores lymphopoiesis in inflammation and aging.Immunity · 2026Article
- Mechanisms coordinating exit from the stem cell state in mammals.Genes & development · 2026Review
- The ageing immune system as a driver of systemic ageing.Nature reviews. Immunology · 2026Review
- Longitudinal lineage tracing reveals early clonal attrition during Drosophila midgut aging.PLoS biology · 2026Article
- Charting single-cell lineages with synthetic and natural barcodes.Nature reviews. Genetics · 2026Review
- Enhancer and metabolic rewiring by KMT2C-COMPASS or KMT2D-COMPASS family loss in cancer creates druggable vulnerabilities.Nature reviews. Cancer · 2026Review
- What sets the mutation rate of a cell type in an animal species?PLoS biology · 2026Article
- A unifying model of stem cell dynamics explains age-related methylation patterns across mammals.Nature aging · 2026Article
- Engineering bone marrow in a dish-a bloody business: preclinical opportunities, translational use cases, and a call for consensus.Journal of thrombosis and haemostasis : JTH · 2026Review
- Insights into the therapeutic strategies for aging and aging-associated diseases.Signal transduction and targeted therapy · 2026Review
- Age-associated hematopoietic variants in the rhesus macaque.Blood advances · 2026Article
- Hematopoietic stem and progenitor cell hierarchy is established by thrombopoietin-driven neonatal hematopoiesis.Stem cell reports · 2026Article
- Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis.Cell stem cell · 2026Article
- Hematopoietic stem cell-independent and -dependent hematopoiesis: new insights and lineage-tracing methods.Experimental hematology · 2026Review
- Hematopoietic (stem) cells-The elixir of life?FEBS letters · 2026Review
- Of Barriers and Loops-How Evolution Limits Most Cancer Risks to Older Ages.Cancer discovery · 2026Review
- SomaMutDB 2.0: A comprehensive database for exploring somatic mutations and their functional impact in normal human tissues.Nucleic acids research · 2026Article
Corrections and comments
- Erratum issued
- Update of
Authors and funding
26 authors.
Chiraag D KapadiaDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-1805-8879
Nicholas WilliamsWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0000-0003-3989-9167
Kevin J DawsonWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Caroline WatsonEarly Cancer Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.ORCID 0000-0002-8351-268X
Matthew J YousefzadehInstitute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0003-2869-1029
Duy LeDepartment of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA.
Kudzai NyamondoWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0009-0008-3312-732X
Sreeya KodavaliWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0009-0000-9335-2475
Alex CaganWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0000-0002-7857-4771
Sarah WaldvogelDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-3657-1951
Xiaoyan ZhangDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
Josephine De La FuenteDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
Daniel LeongamornlertWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0000-0002-3486-3168
Emily MitchellWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Marcus A FlorezDepartment of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA.
Krzysztof SosnowskiWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Rogelio AguilarDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-3569-0713
Alejandra MartellDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
Anna GuzmanDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
David HarrisonThe Jackson Laboratory, Bar Harbor, ME, USA.
Laura J NiedernhoferInstitute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-1074-1385
Katherine Y KingDepartment of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA.
Peter J CampbellWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0000-0002-3921-0510
Jamie BlundellEarly Cancer Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.ORCID 0000-0001-9747-7363
Margaret A GoodellDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. goodell@bcm.edu.ORCID 0000-0003-1111-2932
Jyoti NangaliaWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. jn5@sanger.ac.uk.ORCID 0000-0001-7122-4608
Funding
Interventions That Retard Mammalian AgingU01AG022308 · NIA · JACKSON LABORATORY · PI Ronny Korstanje · 2003 to 2026
$30.5MWnt signaling in muscle stem cell agingP01AG036695 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI THOMAS A. RANDO · 2011 to 2026
$29.3MValidation and characterization of the identified variants associated with human longevity in mouse modelsU19AG056278 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Zhengdong Zhang · 2017 to 2026
$24.5MProject 3: Contribution of inflammation and DNA damaging factors to clonal expansion and malignant transformation in a community cohort of older adultsP01CA265748 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Koichi Takahashi · 2022 to 2026
$13.6MREGULATION OF HEMATOPOIETIC PROGENITORS BY DE NOVO DNA METHYLATIONR01DK092883 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI GOODELL, MARGARET A. · 2012 to 2024
$7.4MDNMT3A in Development of Hematologic MalignanciesR01CA183252 · NCI · BAYLOR COLLEGE OF MEDICINE · PI MARGARET A. GOODELL · 2014 to 2026
$7.1MImpact of Infection and Inflammation on Primitive HematopoiesisR35HL155672 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Katherine Yudeh King · 2021 to 2026
$5.1MPPM1D in Clonal Hematopoiesis and MalignanciesR01CA237291 · NCI · BAYLOR COLLEGE OF MEDICINE · PI MARGARET A. GOODELL, Koichi Takahashi · 2019 to 2026
$3.7MUsing the senolytic fisetin to suppress mortality in aged mice acutely exposed to murine beta-coronavirusR01AG063543 · NIA · UNIVERSITY OF MINNESOTA · PI NIEDERNHOFER, LAURA JANE · 2019 to 2023
$3.4MMicrobiota-dependent regulation of primitive hematopoiesesR01AI141716 · NIAID · WASHINGTON UNIVERSITY · PI BALDRIDGE, MEGAN T · 2019 to 2023
$2.3MRegulation of Hematopoietic Progenitors by de novo DNA MethylationR56DK092883 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI GOODELL, MARGARET A. · 2011 to 2011
$344kDetermining the effect of DNMT3A loss on the competitive fitness of mutant cells in somatic mosaicismF30HD111129 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Sarah Marie Waldvogel · 2023 to 2026
$210kNCI NIH HHS P01 CA265748NCI NIH HHS R01 CA183252NCI NIH HHS R01 CA237291NHLBI NIH HHS F31 HL154661NHLBI NIH HHS F31 HL156500NHLBI NIH HHS R35 HL155672NIAID NIH HHS R01 AI141716NIA NIH HHS P01 AG036695NIA NIH HHS R01 AG063543NIA NIH HHS U01 AG022308NIA NIH HHS U19 AG056278NICHD NIH HHS F30 HD111129NIDDK NIH HHS F30 DK131638NIDDK NIH HHS R01 DK092883NIDDK NIH HHS R56 DK092883Wellcome Trust
Abstract
Haematopoietic stem cells maintain blood production throughout life
Indexed as
Clonal EvolutionClone CellsHematopoiesisHematopoietic Stem CellsAgingAnimalsCell Self RenewalFemaleHumansLongevityMaleMiceMice, Inbred C57BLMultipotent Stem CellsMutationPhylogeny
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.