Evidence map›Paper›PMID 40044395›Full record

ArticleThe American journal of clinical nutrition2025

Phenylketonuria in adults: we know plenty, but there is much more to learn.

Cary O Harding, Georgianne Arnold, Gerard T Berry, Shawn E Christ, Dorothy K Grange, Elaina Jurecki, Harvey Levy, Uta Lichter-Konecki, Nicola Longo, Markey McNutt and 6 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Cary O HardingOregon Health & Science University, Dept. of Molecular and Medical Genetics Portland, OR. Electronic address: hardingc@ohsu.edu.
Georgianne ArnoldChildren's Hospital of Pittsburgh, Dept. of Pediatrics, Pittsburgh, PA.
Gerard T BerryBoston Children's Hospital, Division of Genetics and Genomics, Boston, MA.
Shawn E ChristUniversity of Missouri, Dept. of Psychological Sciences, Columbia, MO.
Dorothy K GrangeWashington University in St. Louis, Dept. of Pediatrics, St. Louis, MO.
Elaina JureckiNational PKU Alliance, San Ramon, CA.
Harvey LevyBoston Children's Hospital, Division of Genetics and Genomics, Boston, MA.
Uta Lichter-KoneckiChildren's Hospital of Pittsburgh, Dept. of Pediatrics, Pittsburgh, PA.
Nicola LongoUniversity of California-Los Angeles, Division of Clinical Genetics, Los Angeles, CA.
Markey McNuttUniversity of Texas Southwestern, Dept. of Internal Medicine, Dallas, TX.
Page MeachumUniversity of Texas Southwestern, Dept. of Internal Medicine, Dallas, TX.
Stephanie SacharowBoston Children's Hospital, Division of Genetics and Genomics, Boston, MA.
Brian ShayotaUniversity of Utah, Depts. of Pediatrics and Medical Genetics, Salt Lake City, UT.
Janet ThomasChildren's Hospital of Colorado, Dept. of Genetics and Inherited Metabolic Diseases, Aurora, CO.
Erika VuckoLurie Children's Hospital, Division of Genetics, Genomics and Metabolism, Chicago, IL.
Members of the PHEFREE Consortium

Funding

Quantitative Measurement of Phenylalanine Metabolism in Sapropterin-Responsive HyperphenylalaninemiaU54HD100982 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI BERRY, GERARD THOMAS · 2019 to 2023
$7.9M
NICHD NIH HHS U54 HD100982
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40044395
PMCPMC12349662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.