Evidence map›Paper›PMID 40044270›Full record

ReviewChild and adolescent psychiatric clinics of North America2025

Preschool Mood Disorders: A Review of the Literature from 2017 to 2024.

Caroline P Hoyniak, Meghan Rose Donohue, Laura Hennefield, Diana J Whalen

Abstract readReview
In one paragraph

Review in Child and adolescent psychiatric clinics of North America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Caroline P HoyniakDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA. Electronic address: choyniak@wustl.edu.
Meghan Rose DonohueDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Laura HennefieldDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Diana J WhalenDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.

Funding

NEUROIMAGING IN EARLY ONSET DEPRESSION: LONGITUDINAL ASSESSMENT OF BRAIN CHANGESR01MH090786 · NIMH · WASHINGTON UNIVERSITY · PI GILBERT, KIRSTEN, WHALEN, DIANA J · 2010 to 2025
$10.4M
Sleep Disturbances and Circadian Misalignment as Potential Markers of Early Childhood DepressionK23MH127305 · NIMH · WASHINGTON UNIVERSITY · PI HOYNIAK, CAROLINE PAIGE · 2021 to 2025
$952k
Neurodevelopmental Emergence of Callous-Unemotional Behavior Beginning in Infancy: Neural Markers and Environmental Risk and Protective FactorsK23MH125023 · NIMH · WASHINGTON UNIVERSITY · PI DONOHUE, MEGHAN ROSE · 2021 to 2025
$904k
Suicidality in Young Children: Social and Cognitive Developmental Markers of Risk and ResiliencyK01MH127412 · NIMH · WASHINGTON UNIVERSITY · PI LAURA HENNEFIELD · 2022 to 2026
$897k
NIMH NIH HHS K01 MH127412NIMH NIH HHS K23 MH125023NIMH NIH HHS K23 MH127305NIMH NIH HHS R01 MH090786
6 · The paper itself

Abstract

Depression symptoms that onset during early childhood are increasingly recognized as a significant public health concern. A proliferation of research over the last 2 decades has identified preschool depression as a diagnostic reality that is associated with a severe and persistent course of depression throughout the lifespan. The current review summarizes the research on preschool depression from the last 7 years (2017-2024), with a particular focus on the assessment of, factors and outcomes associated with, neurobiological underpinnings of, and treatments for preschool depression. We also discuss potential avenues of inquiry that further elucidate the nature of preschool depression.

Indexed as

Mood DisordersChild, PreschoolHumansEarly childhoodMajor depressive disorderPreschool depressionPreschool mood disorders

Identifiers

PMID40044270
PMCPMC11885883

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.