Evidence map›Paper›PMID 40044204›Full record

ArticleBMJ open2025

Impact of hospital-based early detection on management in chronic kidney disease: the CKD Stewardship study (CKD-S) - protocol for a prospective, multicentre, observational cohort study.

Lucinda Alix Wynter, Brendan Smyth, John Saunders, Carmen Moroney, Lilijana Gorringe, Kylie Turner, Sreeram Venugopal, Lisa Tienstra, Rowena Monteverde, Amy Kang and 5 more

Abstract read
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In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lucinda Alix WynterDepartment of Medicine, Canterbury Hospital, Campsie, New South Wales, Australia lucy.wynter@sydney.edu.au.ORCID http://orcid.org/0000-0003-2466-0727
Brendan SmythDepartment of Renal Medicine, St George Hospital, Sydney, New South Wales, Australia.
John SaundersDepartment of Renal Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Carmen MoroneyDepartment of Medicine, Canterbury Hospital, Campsie, New South Wales, Australia.ORCID http://orcid.org/0009-0004-7360-5980
Lilijana GorringeConcord Clinical School, The University of Sydney Faculty of Medicine and Health, Concord, New South Wales, Australia.
Kylie TurnerDepartment of Renal Medicine, St George Hospital, Sydney, New South Wales, Australia.
Sreeram VenugopalDepartment of Renal Medicine, St George Hospital, Sydney, New South Wales, Australia.
Lisa TienstraDepartment of Renal Medicine, Concord Repatriation General Hospital, Concord, New South Wales, Australia.
Rowena MonteverdeDepartment of Renal Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Amy KangDepartment of Nephrology, Prince of Wales Hospital, Randwick, New South Wales, Australia.
Sarah NorrisLeeder Centre for Health Policy, Economics and Data, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-4733-6906
Leyla AouadDepartment of Renal Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Shaundeep SenConcord Clinical School, The University of Sydney Faculty of Medicine and Health, Concord, New South Wales, Australia.
George MangosSt George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
Steven ChadbanDepartment of Renal Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) causes significant morbidity and mortality. Medical therapies can reduce the progression of disease by up to 50%. CKD is undiagnosed in the majority of people who have it, resulting in undertreatment. CKD Stewardship (CKD-S) aims to identify hospital inpatients with undiagnosed mid-stage to late-stage CKD with the goal of facilitating diagnosis and initiating guideline-based therapies. METHODS AND ANALYSIS: This prospective, multicentre, cohort study compares two models of care, CKD-S and standard care, for identification and management of CKD, across six public hospitals in metropolitan Sydney, Australia. CKD-S entails active case finding using the electronic medical record, with nephrologist outreach to admitting teams and kidney nurse provided patient education. Adult inpatients with an admission estimated glomerular filtration rate (eGFR)<45 mL/min/1.73 m ETHICS AND DISSEMINATION: The study has ethics approval from the Sydney Local Health District's Ethics Committee (Concord Hospital Zone). The results of the CKD-S study will be published in peer-reviewed journals and presented at academic conferences. TRIAL REGISTRATION NUMBER: ACTRN12624000452594.

Indexed as

Early DiagnosisRenal Insufficiency, ChronicAustraliaFemaleGlomerular Filtration RateHospitalizationHumansMaleMulticenter Studies as TopicObservational Studies as TopicProspective StudiesChronic renal failureEnd stage renal failureMass Screening

Identifiers

PMID40044204
PMCPMC11883606

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.