ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2025
Heart donation and transplant recipient survival outcomes from deceased organ donors managed in hospital-based vs independent donor care units.
Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundDespite growing prevalence, the impact of centralized deceased organ donor care units on heart donation and transplant recipient outcomes remains unknown.
methodsWe conducted a retrospective study using Organ Procurement and Transplantation Network deceased donor and transplant recipient data. We included adult deceased organ donors after brain death managed in 21 US regions with donor care units (DCUs) January 2019 to December 2022 and their heart recipients. The primary exposure was organ recovery in independent vs hospital-based DCUs. Outcomes included heart graft survival duration (primary) and incidence of heart donation.
resultsThe cohort captured 9,830 donors after brain death, 3,302 in 10 independent DCUs (33.6%), and 1,366 (13.9%) in 11 hospital-based DCUs (the remainder in hospitals). Unadjusted heart donation did not differ between independent and hospital-based DCUs (40.9% vs 40.4%, p = 0.75). In a logistic regression model including donor factors, odds of heart donation did not differ by DCU type (adjusted odds ratio [aOR] 1.02, 95% confidence interval [CI] 0.86-1.22). Among 3,108 heart transplant recipients from cohort heart donors, restricted mean survival time 4 years after transplant was not different between hearts recovered in independent vs hospital-based DCUs (1,292 vs 1,276 days). In a Cox model including donor and recipient factors, adjusted hazards of graft failure were not different by DCU type (adjusted hazard ratio [aHR] 0.79, 95% CI 0.50-1.24).
conclusionsAmong deceased organ donors after brain death, heart donation and heart transplant survival did not vary between hospital-based and independent DCUs. Further work is needed to determine if DCU utilization increases the number of hearts available for transplant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.