Evidence map›Paper›PMID 40043221›Full record

ArticleJCO clinical cancer informatics2025

Preoperative Maximum Standardized Uptake Value Emphasized in Explainable Machine Learning Model for Predicting the Risk of Recurrence in Resected Non-Small Cell Lung Cancer.

Takafumi Iguchi, Kensuke Kojima, Daiki Hayashi, Toshiteru Tokunaga, Kyoichi Okishio, Hyungeun Yoon

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takafumi IguchiDepartment of General Thoracic Surgery, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.ORCID 0000-0002-2067-223X
Kensuke KojimaDepartment of General Thoracic Surgery, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.ORCID 0000-0001-8136-4970
Daiki HayashiDepartment of General Thoracic Surgery, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.
Toshiteru TokunagaDepartment of General Thoracic Surgery, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.
Kyoichi OkishioClinical Research Center, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.ORCID 0000-0002-6348-1302
Hyungeun YoonDepartment of General Thoracic Surgery, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo comprehensively analyze the association between preoperative maximum standardized uptake value (SUV PATIENTS AND

methodsThis retrospective study included 643 patients who had undergone NSCLC resection. ML models (random forest, gradient boosting, extreme gradient boosting, and AdaBoost) and a random survival forest model were developed to predict postoperative recurrence. Model performance was evaluated using the receiver operating characteristic (ROC) AUC and concordance index (C-index). Shapley additive explanations (SHAP) and partial dependence plots (PDPs) were used to interpret model predictions and quantify feature importance. The relationship between SUV

resultsThe random forest model showed the highest predictive performance (ROC AUC, 0.90; 95% CI, 0.86 to 0.97). The SHAP analysis identified SUV

conclusionPreoperative SUV

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMachine LearningNeoplasm Recurrence, LocalAgedFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPositron Emission Tomography Computed TomographyPreoperative PeriodPrognosisRetrospective StudiesROC CurveFluorodeoxyglucose F18

Identifiers

PMID40043221
PMCPMC11902606

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.