Evidence map›Paper›PMID 40042700›Full record

ArticleBrain imaging and behavior2025

The neuroprotective power of artificial liver therapy: reversing cognitive impairment in minimal hepatic encephalopathy.

Xiaodong Wang, Xuhong Yang, Minglei Wang, Xueying Huang, Ming Zhang

Abstract read
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In one paragraph

Article in Brain imaging and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaodong Wang *Xi'an Jiaotong University, Department of Medical Imaging, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Xuhong Yang *Jiangsu Key Laboratory of Molecular Imaging and Functional Imaging, Medical School of Southeast University, 87 Dingjiaqiao, Nanjing, 210009, China.
Minglei WangDepartment of Radiology, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Xueying HuangDepartment of Radiology, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Ming ZhangXi'an Jiaotong University, Department of Medical Imaging, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China. zhangming01@xjtu.edu.cn.

Funding

Natural Science Foundation of Ningxia Province 2022AAC03487Science and Technology Key Research Program of Ningxia 2019BEG03037
6 · The paper itself

Abstract

Alteration of functional connectivity in brain regions is one of the potential neuropathological mechanisms underlying cognitive impairment in patients with minimal hepatic encephalopathy (MHE). Artificial liver therapy has been shown to improve cognitive impairment in patients, suggesting a potential neuroprotective effect on the brain. This study investigates the impact of artificial liver therapy (AL) on cognitive impairment in patients with minimal hepatic encephalopathy (MHE) by examining alterations in brain functional connectivity. Resting-state functional magnetic resonance imaging (fMRI) data was collected from healthy controls and MHE patients before and after therapy. The MHE

Indexed as

Cognitive DysfunctionHepatic EncephalopathyLiver, ArtificialAdultBrainCognitionExecutive FunctionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysNeuropsychological TestsArtificial liverCognitive impairmentFunctional connectivityInsulaMinimal hepatic encephalopathy

Identifiers

PMID40042700

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.