ArticleVirchows Archiv : an international journal of pathology2025
EWSR1::BEND2 fusion sarcoma in bone: a report of two rare cases.
Article in Virchows Archiv : an international journal of pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- A pediatric low-grade sinonasal mesenchymal tumor harboring a novel CHD9::BEND2 fusion.Virchows Archiv : an international journal of pathology · 2025Article
- EWSR1::BEND2 fusion sarcoma of the urinary bladder - a case report and review of literature.Diagnostic pathology · 2025Review
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Authors and funding
7 authors.
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Abstract
The two cases, we had presented here, were extremely rare instances of the EWSR1::BEND2 fusion sarcomas in bone. The first case was a 12-year-old female with a 50 × 25-mm lytic tumor in metatarsal bone. Histopathologic examination revealed a widespread cellular, fascicular forming, spindled cell component along with a focal round cell component. CD99 was diffuse membranous positive while cytokeratin and EMA were focal positive. The second case was a 62-year-old female with a pathological fracture in femur. On MRI examination, a heterogeneous tumor measuring 96 × 54 mm was detected in the femur, extending into the soft tissue. Histopathologic examination revealed a high-grade lesion consisting of round cells. CD56, CD99, and cytokeratin were focal positive. EWSR1::BEND2 fusion has previously been reported in a subtype of astroblastoma and other rare entities that we discuss in this work.
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