ArticleDie Ophthalmologie2025
[Neurotrophic keratopathy and corneal ulcers in diabetes mellitus].
Article in Die Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is a chronic metabolic disease associated with numerous complications, including diabetic keratopathy. This frequently underestimated disease can lead to reduced corneal sensitivity, neurotrophic ulcers and potentially sight-threatening infections. In this retrospective analysis of the subgroup of 136,992 machine-readable health records recruited from all patients who presented to our university outpatient clinic between January 2003 and February 2024, we investigated the association between diabetes mellitus, neurotrophic keratopathy and corneal ulcers. Of the patients 3168 had corneal ulcers (prevalence 2.3%) and 11,338 had diabetes mellitus (8%). The results showed that diabetes mellitus significantly increased the risk of corneal ulcers (odds ratio, OR 1.18; 95% confidence interval, CI 1.04-1.32) and neurotrophic keratopathy (OR 1.78; 95% CI 1.20-2.56). In addition, older age and male gender were risk factors. In the reverse analysis, corneal ulcers were shown to be significant predictors of the presence of diabetes mellitus. Our results underline the need for regular ophthalmological check-ups and diabetes mellitus screening in patients with corneal complications in order to intervene at an early stage and prevent severe consequences such as loss of vision.
Indexed as
Identifiers
40042660What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.