Evidence map›Paper›PMID 40042642›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Age-related prevalence of radiographic lumbar spondylolisthesis and its associations with low back pain, walking speed, and muscle index: findings from the second survey of the ROAD study.

Satoshi Arita, Yuyu Ishimoto, Hiroshi Hashizume, Keiji Nagata, Masatoshi Teraguchi, Shigeyuki Muraki, Hiroyuki Oka, Masanari Takami, Shunji Tsutsui, Hiroshi Iwasaki and 9 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Satoshi AritaDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Yuyu IshimotoDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan. sekitui@wakayama-med.ac.jp.
Hiroshi HashizumeDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Keiji NagataDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Masatoshi TeraguchiDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Shigeyuki MurakiDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Hiroyuki OkaDepartment of Medical Research and Management for Musculoskeletal Pain 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Masanari TakamiDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Shunji TsutsuiDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Hiroshi IwasakiDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Toshiko IidakaDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Toru AkuneNational Rehabilitation Center for Persons with Disabilities, Tokorosawa-shi, Japan.
Hiroshi KawaguchiNadogaya Hospital, Kashiwa-shi, Japan.
Sakae TanakaDepartment of Orthopedic Surgery, Sensory and Motor System Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kozo NakamuraTowa Hospital, Tokyo, Japan.
Munehito YoshidaDepartment of Orthopaedic Surgery, Sumiya Orthopaedic Hospital, Wakayama City, Japan.
Noriko YoshimuraDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.
Hiroshi YamadaDepartment of Orthopedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.
Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the prevalence of lumbar spondylolisthesis (LS) and its association with low back pain, walking speed, grip strength, and muscle mass in the general population.

methodsParticipants included 1551 members of the general population from the 2nd ROAD (Research on Osteoarthritis/osteoporosis Against Disability) study conducted in Wakayama Prefecture, Japan, between 2008 and 2010. Lumbar radiography diagnosed LS when the slip was ≥ 3 mm in the lateral views. Logistic regression analysis (adjusted for sex, age, area, and BMI) assessed the association between LS and low back pain, walking speed, grip strength, and appendicular lean mass.

resultsComplete data from 1522 participants (510 men, 1012 women, mean age 65.7 ± 12.2 years) were analyzed. The prevalence of LS increases with age, with an estimated one in five men aged 80 years or older and one in four women aged 70-79 years affected. Logistic regression showed LS was significantly associated with low back pain (OR: 1.36, CI: 1.03-1.80). Walking speed, grip strength, and appendicular lean mass were not significantly associated with LS. The prevalence of LS at any level was 17.4% in the total sample, 13.3% in men, and 19.5% in women (P = 0.005).

conclusionLS was prevalent in 17.4% of the general population, with a higher prevalence in women. Patients with LS had more low back pain than those without LS.

Indexed as

Low Back PainLumbar VertebraeSpondylolisthesisWalking SpeedAdultAgedAged, 80 and overAge FactorsFemaleHand StrengthHumansJapanMaleMiddle AgedPrevalenceRadiographyAppendicular lean massLow back painLumbar spondylolisthesisPrevalenceWalking speed

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.