Evidence map›Paper›PMID 40042573›Full record

Trial reportEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2025

Comparison of retention rates of silver nanoparticles-based fissure sealant and conventional resin-based sealant: a one-year randomized clinical trial.

S Svetha, K Bansal, V P Mathur, N Tewari, R Morankar, M Kalaivani

Abstract readRandomized Controlled TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S SvethaDepartment of Pediatric and Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, 110029, India.
K BansalDepartment of Pediatric and Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, 110029, India. drkalpanabansal@gmail.com.ORCID http://orcid.org/0000-0003-4503-5234
V P MathurDepartment of Pediatric and Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, 110029, India.
N TewariDepartment of Pediatric and Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, 110029, India.
R MorankarDepartment of Pediatric and Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, 110029, India.
M KalaivaniDepartment of Biostatistics, All India Institute of Medical Sciences, New Delhi, 110029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited clinical evidence is currently available on the retention rates of the silver-nanoparticles filled pit and fissure sealant in permanent molars.

aimTo compare the retention rates of a resin-based sealant with silver-nanoparticles with that of a conventional resin-based sealant on permanent molars in children.

methodsA split-mouth design was used. Six to fourteen years old children (n = 150) reporting to a tertiary care hospital were recruited. A total of 264 pairs of permanent molars were subjected to one of the two interventions-A-Resin-based sealant without silver-nanoparticles (Helioseal F plus sealant); B-resin-based sealant with silver-nanoparticles (e-pit and fissure sealant). Sealants were applied using a standardized technique by a single-blinded operator. Primary outcome was the retention of the sealants and secondary outcomes were the presence or absence of caries, surface roughness, marginal integrity and discoloration of the sealant material. Follow-up evaluations were conducted at 6- and 12-months by two blinded evaluators. Data were analysed using the Chi-square test and p-value less than 0.05 was considered to be significant.

resultsAt 12 months, 224 pairs of permanent molars were available for analysis. The test sealant, e-Pit and fissure sealant performed better in terms of retention (68.3% of sealants with silver-nanoparticles retained as compared to 53.6% of resin-based sealants Helioseal F plus; p = 0.001), surface roughness, marginal integrity and sealant discoloration (p < 0.05). The occurrence of caries did not differ significantly between the two groups (p = 0.391).

conclusionThe study concluded that e-pit and fissure sealant with silver-nanoparticles had a better retention rate as compared to the Helioseal F plus sealant but caries occurrence was not different between the two groups. TRIAL REGISTRATION NUMBER: CTRI/2022/05/042622.

Indexed as

Metal NanoparticlesPit and Fissure SealantsSilverAdolescentChildComposite ResinsDental CariesFemaleHumansMaleMolarSingle-Blind MethodComposite ResinsHeliosealPit and Fissure SealantsSilverCariologyClinical trialDental materialsFissure sealantSilver nanoparticles

Identifiers

PMID40042573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.