ReviewNaunyn-Schmiedeberg's archives of pharmacology2025
The appearance of bitter taste receptors - inspiration from structure, expression, function, and mechanism.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Bitter taste receptors belong to the class A of the GPCR superfamily of G protein-coupled receptors. Bitter taste receptors have different numbers and structures in different species, and an analysis of their structures facilitates the discovery and development of their agonists and inhibitors. In addition, bitter taste receptors differ in expression between species and tissues, which corresponds to the diversity and specificity of their mechanisms of action. At present, bitter taste receptors also have a wide range of effects on the treatment of diseases, including gastrointestinal, airway, heart, orthopedic, urinary disease, and cancer. Therefore, this article reviewed the structure, expression, function, and mechanism of bitter taste receptors, in order to develop more bitter taste receptors and bitter ligands for treatment, and provide some new ideas and goals for the clinical use of bitter drugs.
Indexed as
Identifiers
40042562What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.