Evidence map›Paper›PMID 40042368›Full record

ArticleEmerging microbes & infections2025

Sharp rise in high-virulence Bordetella pertussis with macrolides resistance in Northern China.

Yahong Hu, Lin Zhou, Qianqian Du, Wei Shi, Qinghong Meng, Lin Yuan, Huili Hu, Lijuan Ma, Dongfang Li, Kaihu Yao

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Comment on "sharp rise in high-virulenceEmerging microbes & infections · 2026
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  3. Review
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  16. Waning immunity, prevailing non-vaccine typeThe Lancet regional health. Western Pacific · 2025
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yahong HuKey Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing PaediatricPediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Lin ZhouDepartment of Clinical Laboratory, Capital Institute of, Beijing, People's Republic of China.
Qianqian DuKey Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing PaediatricPediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Wei ShiKey Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing PaediatricPediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Qinghong MengKey Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing PaediatricPediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Lin YuanKey Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing PaediatricPediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Huili HuDepartment of Pediatrics, Beijing Shijingshan Hospital, Shijingshan Teaching Hospital, Capital Medical University, Beijing, People's Republic of China.
Lijuan MaDepartment of Clinical Laboratory, Capital Institute of, Beijing, People's Republic of China.
Dongfang LiBGI, Shenzhen, People's Republic of China.
Kaihu YaoKey Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing PaediatricPediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo elucidate the evolution of antigen genotype and antimicrobial resistance distribution of

methodsPolymerase chain reaction (PCR) amplification and sequencing were utilized to identify the seven antigen genotypes (

resultsA total of 442

conclusionsThese results suggested the clonal spread of the

Indexed as

Anti-Bacterial AgentsBordetella pertussisDrug Resistance, BacterialMacrolidesWhooping CoughAdolescentChildChild, PreschoolChinaFemaleGenotypeHumansInfantMaleMicrobial Sensitivity TestsMultilocus Sequence TypingAnti-Bacterial AgentsMacrolidesBordetella pertussisChinaErythromycin resistanceMT28Ptxp3

Identifiers

PMID40042368
PMCPMC11921162

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.