Evidence map›Paper›PMID 40042325›Full record

ArticleMicrobiology spectrum2025

The role of autoantibodies in post-chikungunya viral arthritis disease severity.

Samantha Ansah-Dico, Ilana Heckler, Michelle Premazzi Papa, Alfonso Sucerquia Hernández, Jose Forero Mejía, Sarah Renee Tritsch, Evelyn Mendoza-Torres, Liliana Encinales, Andres Cadena Bonfanti, Abigale Marie Proctor and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Samantha Ansah-DicoDepartment of Microbiology, Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, USA.
Ilana HecklerDepartment of Scientific Affairs, EUROIMMUN US, Mountain Lakes, New Jersey, USA.
Michelle Premazzi PapaDepartment of Microbiology, Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, USA.
Alfonso Sucerquia HernándezDepartment of Medicine, George Washington University, Washington, D.C., USA.
Jose Forero MejíaDepartment of Medicine, George Washington University, Washington, D.C., USA.
Sarah Renee TritschGlobal Health, Milken Institute School of Public Health, George Washington University, Washington, D.C., USA.
Evelyn Mendoza-TorresAdvanced Biomedicine Research Group, Faculty of Health, Exact and Natural Sciences, Universidad Libre de Colombia, Barranquilla, Atlantico, Colombia.
Liliana EncinalesDepartment of Medicine, Allied Research Society, Barranquilla, Atlántico, Colombia.
Andres Cadena BonfantiCentro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Abigale Marie ProctorGlobal Health, Milken Institute School of Public Health, George Washington University, Washington, D.C., USA.
Jessica M WellsDepartment of Quality Operations, EUROIMMUN US, Mountain Lakes, New Jersey, USA.
Daniela Díaz HernándezPediatrics Department, Faculty of Health, Exact and Natural Sciences, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Juan Manuel Pretelt GazabonInternal Medicine Department. Faculty of Health, Exact and Natural Sciences, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Mónica Gómez PulidoMicrobiology Department. Faculty of Health, Exact and Natural Sciences, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Sara Camila Castiblanco-ArroyaveInternal Medicine Department. Faculty of Health, Exact and Natural Sciences, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Sammuel Joseph SimmensDepartment of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University Milken Institute School of Public Health, Washington, D.C., USA.
Rebecca LynchDepartment of Microbiology, Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, USA.
Aileen Yu-Hen ChangDepartment of Microbiology, Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, USA.ORCID 0000-0001-7410-9867

Funding

The role of IL-2 therapy for Relapsing-Remitting Chikungunya ArthritisK23AR076505 · NIAMS · GEORGE WASHINGTON UNIVERSITY · PI CHANG, AILEEN · 2020 to 2022
$466k
NIAMS NIH HHS K23 AR076505
6 · The paper itself

Abstract

Post-chikungunya viral arthritis may persist for months to years after infection and is characterized by relapsing and remitting symptoms. This study investigates the relationship between autoantibodies and chikungunya arthritis severity, providing insights into arthritis pathogenesis. We assessed arthritis measures in a cohort of serologically confirmed chikungunya cases from Colombia between 2019 and 2021 (

Indexed as

AutoantibodiesChikungunya FeverAdultAgedAnti-Citrullinated Protein AntibodiesChikungunya virusColombiaFemaleHumansImmunoglobulin MMaleMiddle AgedRheumatoid FactorSeverity of Illness IndexYoung AdultAnti-Citrullinated Protein AntibodiesAutoantibodiesImmunoglobulin MRheumatoid Factorantibodiesarthritisarthritis disease severityautoantibodieschikungunya virus

Identifiers

PMID40042325
PMCPMC11960447

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.