Evidence map›Paper›PMID 40042276›Full record

ArticleApplied and environmental microbiology2025

Microbial magnetite oxidation via MtoAB porin-multiheme cytochrome complex in

Jessica L Keffer, Nanqing Zhou, Danielle D Rushworth, Yanbao Yu, Clara S Chan

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Deciphering the Mto electron uptake pathway ofApplied and environmental microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. An organotrophicApplied and environmental microbiology · 2025
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jessica L KefferDepartment of Earth Sciences, University of Delaware, Newark, Delaware, USA.ORCID 0000-0002-0302-3588
Nanqing ZhouSchool of Marine Science and Policy, University of Delaware, Newark, Delaware, USA.ORCID 0000-0002-8815-6274
Danielle D RushworthDepartment of Earth Sciences, University of Delaware, Newark, Delaware, USA.
Yanbao YuDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware, USA.ORCID 0000-0003-2994-1974
Clara S ChanDepartment of Earth Sciences, University of Delaware, Newark, Delaware, USA.ORCID 0000-0003-1810-4994

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Shawn W Polson · 2012 to 2026
$67.2M
This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
HHS | National Institutes of Health (NIH) P20GM103446HHS | National Institutes of Health (NIH) P20GM104316National Science Foundation (NSF) BIO-1817651NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P20 GM104316
6 · The paper itself

Abstract

Most of Earth's iron is mineral-bound, but it is unclear how and to what extent iron-oxidizing microbes can use solid minerals as electron donors. A prime candidate for studying mineral-oxidizing growth and pathways is IMPORTANCE: Mineral-bound iron could be a vast source of energy to iron-oxidizing bacteria, but there is limited physiological evidence of this metabolism, and it has been unknown whether the mechanisms of solid and dissolved Fe(II) oxidation are distinct. In iron-reducing bacteria, multiheme cytochromes can facilitate iron mineral reduction, and here, we link a multiheme cytochrome-based pathway to mineral oxidation, expanding the known functionality of multiheme cytochromes. Given the growing recognition of microbial oxidation of minerals and cathodes, increasing our understanding of these mechanisms will allow us to recognize and trace the activities of mineral-oxidizing microbes. This work shows how solid iron minerals can promote microbial growth, which, if widespread, could be a major agent of geologic weathering and mineral-fueled nutrient cycling in sediments, aquifers, and rock-hosted environments.

Indexed as

Bacterial ProteinsCytochromesFerrosoferric OxideSulfolobaceaeIronOxidation-ReductionBacterial ProteinsCytochromesFerrosoferric OxideIronGallionellaceaeiron oxidizersmagnetitemicrobe-mineral interactionsmultiheme cytochromesSideroxydans

Identifiers

PMID40042276
PMCPMC12016527

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.