ArticleFrontiers in microbiology2025
Rumen-protected guanidinoacetic acid improves growth performance in beef cattle under chronic heat stress by reshaping gut microbiota and modulating serum metabolism.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Methionine and guanidinoacetic acid supplementation throughout the periconceptual period of gestation altered metabolite concentrations and fetal development in beef heifers.Journal of animal science · 2026Article
- Rumen-protected guanidinoacetic acid is associated with improved growth performance and altered portal nutrient and hepatic IGF-1 indices in Hu sheep.Frontiers in veterinary science · 2026Article
- Effects on Rumen Microbial Population and Serum Biochemical Responses to Guanidinoacetic Acid,Animals : an open access journal from MDPI · 2025Article
- Integrated transcriptomic and phenotypic analysis reveals tissue-specific regulatory effects of guanidinoacetic acid in cattle.BMC genomics · 2025Article
- Effect of guanidinoacetic acid on the growth performance, serum biochemical indices and metabolites, intestinal morphology, and intestinal flora of Cherry Valley broiler ducks.Poultry science · 2025Article
- Innovations in Cattle Breeding Technology: Prospects in the Era of Gene Editing.Animals : an open access journal from MDPI · 2025Review
- Guanidinoacetic Acid and Its Impact on the Performance, Carcass and Meat Quality of Growing and Finishing Nellore Cattle.Veterinary sciences · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate the effects of rumen-protected guanidinoacetic acid (RP-GAA) on growth performance, gut microbiota, and serum metabolism in beef cattle under chronic heat stress. A randomized block design was employed to allocate 14 F1 Simmental crossbred cattle (Simmental ♂ ×
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.