Evidence map›Paper›PMID 40041820›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2025

Visualization of Trochlear Dysplasia Using 3-Dimensional Curvature Analysis in Patients With Patellar Instability Facilitates Understanding and Improves the Reliability of the Entry Point to Trochlea Groove Angle.

Johannes M Sieberer, Nancy Park, Armita R Manafzadeh, Shelby T Desroches, Kelsey Brennan, Curtis McDonald, Steven M Tommasini, Daniel H Wiznia, John P Fulkerson

Registry-linked trialAbstract read
In one paragraph

Article in Arthroscopy, sports medicine, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07472088 (Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07472088 recruitingnot on this mapstarted 2026, after this paper: background citation

Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms

TypeobservationalSponsorUniversity of Kansas Medical CenterRan2026 to 2026Enrolled36ConditionsKnee Osteoarthritis, Patellofemoral Pain (PFPS)ArmsWBCT
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johannes M SiebererDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, U.S.A.
Nancy ParkDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, U.S.A.
Armita R ManafzadehYale Institute for Biospheric Studies, Yale University, New Haven, Connecticut, U.S.A.
Shelby T DesrochesDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, U.S.A.
Kelsey BrennanDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, U.S.A.
Curtis McDonaldDepartment of Statistics and Data Science, Yale University, New Haven, Connecticut, U.S.A.
Steven M TommasiniDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, U.S.A.
Daniel H WizniaDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, U.S.A.
John P FulkersonDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, U.S.A.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Purpose: To examine a method to visualize a 3-dimensional (3D) rendered distal femur using 3D curvature analysis and to compare models of patellofemoral instability (PFI) with controls to study the reliability of the entry point to trochlear groove angle (EPTG) metric. Methods: The 3D models of patients with recurrent patellar instability, defined by at least 2 reported patellar dislocation events, and age- and sex-matched controls were created from computed tomography scans. Curvature was calculated to highlight the proximal trochlear ridges and the trochlear groove by overlaying them on the 3D models. Anteroposterior views with and without curvature visualization were created and used for qualitative comparison and to measure the EPTG. The EPTG was measured by 2 raters with and without the aid of the curvature maps. Significant differences between patients with PFI and controls were compared with a Mann-Whitney Results: Qualitive analysis between 30 PFI patient knees (age: 23.9 ± 8.4 years, female/male: 24/6) and 30 control knees (age: 21.8 ± 5.6 years, female/male: 22/8) showed that in general, patients with PFI have a lateralized medial ridge and trochlear groove, with the trochlear groove being shorter and shallower. Qualitatively, differences between patients with PFI and controls were significant for measurements both with and without the aid of the curvature maps. Inter-rater reliability was significantly ( Conclusions: Curvature-based visualization aids overlain on a 3D model have the power to increase the information gained from 3D imaging and corresponding 3D models, amplifying their potential value in clinical decision-making. Such visualizations facilitate both the identification of qualitative differences between patient and control morphology and improve the reliability of the EPTG trochlear dysplasia metric. Level of Evidence: Level III, retrospective cohort study.

Identifiers

PMID40041820
PMCPMC11873473

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.