Evidence map›Paper›PMID 40041477›Full record

ArticleSleep advances : a journal of the Sleep Research Society2025

Layover start timing predicts layover sleep quantity and timing on long-range and ultra-long-range trips.

Michael J Rempe, Ian Rasmussen, Kevin Gregory, Cheyenne Johnson, Matthew Hsin, Erin Flynn-Evans, Amanda Lamp, Cassie J Hilditch

Registry-linked trialAbstract read
In one paragraph

Article in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07761611 (Evaluation of Fatigue and Mitigations During Long-haul Operations), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07761611 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of Fatigue and Mitigations During Long-haul Operations

TypeinterventionalSponsorNational Aeronautics and Space Administration (NASA)Ran2026 to 2029Enrolled118ConditionsAlertness, Fatigue, Mood, and Performance, Calorie Restriction and Light InterventionArmsCaloric restriction, Light exposure
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael J RempeDepartment of Translational Medicine and Physiology, Washington State University, Spokane, WA, USA.
Ian RasmussenDepartment of Translational Medicine and Physiology, Washington State University, Spokane, WA, USA.
Kevin GregoryFatigue Countermeasures Laboratory, Human Systems Integration Division, NASA Ames Research Center, Moffett Field, CA, USA.
Cheyenne JohnsonDepartment of Translational Medicine and Physiology, Washington State University, Spokane, WA, USA.
Matthew HsinDepartment of Translational Medicine and Physiology, Washington State University, Spokane, WA, USA.
Erin Flynn-EvansFatigue Countermeasures Laboratory, Human Systems Integration Division, NASA Ames Research Center, Moffett Field, CA, USA.
Amanda LampDepartment of Translational Medicine and Physiology, Washington State University, Spokane, WA, USA.
Cassie J HilditchFatigue Countermeasures Laboratory, Department of Psychology, San José State University, San José, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study Objectives: Airline transport pilot sleep during layover is an important factor for alertness on subsequent flights. Assessing pilots' sleep on layover is an important first step in helping them obtain the most recuperative sleep possible on layover. Here, we investigate the quantity and timing of sleep during layovers and determine predictors for layover sleep. Methods: Sleep was assessed in 256 pilots flying a total of 473 long-range (LR; flight time 12-16 hours) or ultra-long-range (ULR; flight time Results: Overall, pilots averaged 7.2 hours of sleep per 24 hours of layover, which was significantly less than their daily sleep before or after the trip. Layover start time (relative to home base time) was the most salient predictor of sleep timing and quantity during both shorter (∼24-hour) and the first 24 hours of longer (∼48-hour) layovers. During the last 24 hours of longer layovers, crew type predicted sleep quantity. Conclusions: Although average sleep quantity during layovers was within the margins of recommended sleep duration, it was still less than pre- and post-trip sleep duration, suggesting modest sleep loss on layovers. Layover start timing was the strongest predictor of layover sleep quantity and timing and, thus, may be a modifiable factor to protect circadian-aligned sleep opportunities during layover.

Indexed as

aviationlayoverlong-rangepilotsrecovery sleepultra-long-range

Identifiers

PMID40041477
PMCPMC11879054

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.