ArticleJournal of clinical imaging science2025
Basic verification of myocardial extracellular volume quantification by prototype photon-counting detector computed tomography: A phantom study.
Article in Journal of clinical imaging science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cardiac imaging using photon counting CT - benefits, challenges and prospects.The international journal of cardiovascular imaging · 2026Review
- Dual-energy based myocardial extracellular volume quantification with photon-counting detector and energy-integrating detector dual-source computed tomography: comparison with cardiac magnetic resonance.European radiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aimed to investigate the accuracy of myocardial extracellular volume (ECV) quantification using a prototype photon-counting detector (PCD) computed tomography (CT) and examine the association between radiation dose and spectral image settings. Material and Methods: A multi-energy CT phantom that simulated the blood pool and myocardium was used. The tube voltage was set at 120 kVp and three types of tube current-time products (105, 150, and 300 mAs) were applied for pre- and post-contrast scans. Virtual monoenergetic images (VMIs) at 50-100 keV were reconstructed. The ECV value was calculated from the CT numbers between pre-contrast and post-contrast. We compared the accuracy of ECV values at each VMI level. Results: Each radiation dose setting demonstrated a small but significant difference in ECV values at each keV level. ECV was overestimated at higher keV in all radiation dose settings. A significant difference in ECV value variabilities was found among keV levels in all three radiation dose settings, with higher keV exhibiting greater variability. The variation was particularly large in the low-dose setting. The residual values were significantly larger at higher keV levels in all radiation dose settings. The residual values were smaller at 50 and 60 keV with no significant difference in 150- and 300-mAs settings. Conclusion: Setting appropriate VMI keV and radiation dose settings was necessary when quantifying myocardial ECV with PCD-CT because the keV levels caused differences in the quantification value and measurement variation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.