Evidence map›Paper›PMID 40041423›Full record

ReviewFrontiers in behavioral neuroscience2025

Efficacy of vigorous physical activity as an intervention for mitigating depressive symptoms in adolescents and young adults: a comprehensive systematic review and meta-analysis.

Wei Yang, Huijing Chen, Wei Liu, Sheng Qu, Yao Ge, Jin Song

Abstract readReview
In one paragraph

Review in Frontiers in behavioral neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei YangPsychiatric Rehabilitation Ward 2, Wuhan Mental Health Center, Wuhan, China.
Huijing ChenPsychiatric Rehabilitation Ward 2, Wuhan Mental Health Center, Wuhan, China.
Wei LiuPsychiatric Rehabilitation Ward 2, Wuhan Mental Health Center, Wuhan, China.
Sheng QuPsychiatric Rehabilitation Ward 2, Wuhan Mental Health Center, Wuhan, China.
Yao GePsychiatric Rehabilitation Ward 2, Wuhan Mental Health Center, Wuhan, China.
Jin SongPsychiatric Rehabilitation Ward 2, Wuhan Mental Health Center, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the effectiveness of vigorous physical activity as an intervention for alleviating depressive symptoms among adolescents and young adults. Methods: A comprehensive search on systematically reliable databases was carried out, and studies running till August 2023 were considered in this study. The articles included in this meta-analysis assessed the impact of exercise interventions on depressive symptomatology in adolescents and young adults. Two independent investigators screened the studies, extracted data, and evaluated quality. Results: Physical activity produced an important reduction in depressive symptoms [SMD] = -4.23, 95% CI: -7.02, -1.44, Conclusion: This meta-analysis suggests that vigorous physical activity could reduce depressive symptoms in adolescents and young adults. However, further studies are needed to provide clearer recommendations regarding the type, duration, and intensity of exercise necessary to treat clinical depression in this population.

Indexed as

adolescentdepressionmeta-analysisphysical activityrandomized controlled trialsystematic review

Identifiers

PMID40041423
PMCPMC11876554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.