Evidence map›Paper›PMID 40041422›Full record

ArticlePrecision clinical medicine2025

Spatially defined intratumoral immune biomarkers predict recurrent versus second primary tumors in non-small cell lung cancer.

Rekha Mudappathi, Alanna Maguire, Eunhee S Yi, Yanmei Peng, Jennifer M Kachergus, Andras Khoor, Kexin Tan, Isabella Zaniletti, Jason A Wampfler, Yanyan Lou and 9 more

Abstract read
In one paragraph

Article in Precision clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Rekha MudappathiDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ 85259, USA.
Alanna MaguireDepartment of Cancer Biology, Mayo Clinic, Scottsdale, AZ 85259, USA.
Eunhee S YiDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Yanmei PengDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ 85259, USA.
Jennifer M KachergusDepartment of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA.
Andras KhoorDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL 32224, USA.
Kexin TanDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ 85259, USA.
Isabella ZanilettiIZ Statistics LLC, Tampa, FL 33647, USA.
Jason A WampflerDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Yanyan LouDepartment of Oncology, Mayo Clinic, Jacksonville, FL 32224, USA.
Pedro A Reck Dos SantosDepartment of Cardiothoracic Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.
Jonathan D'CunhaDepartment of Hematology/Oncology, Mayo Clinic, Jacksonville, FL 32224, USA.
Zhifu SunDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Li LiuCollege of Health Solutions, Arizona State University, Phoenix , AZ 85004, USA.ORCID https://orcid.org/0000-0003-4002-7497
Diane F JelinekDepartment of Immunology, Mayo Clinic, Scottsdale, AZ 85259, USA.
Junwen WangDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ 85259, USA.ORCID https://orcid.org/0000-0002-4432-4707
Henry D TazelaarDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ 85259, USA.
E A ThompsonDepartment of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA.
Ping YangDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ 85259, USA.ORCID https://orcid.org/0000-0002-8588-847X

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI AKHILESH PANDEY · 1985 to 2026
$151.3M
NCI NIH HHS P30 CA015083
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40041422
PMCPMC11878774

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.