ArticleRSC advances2025
Supradecoration induced homogenous electrochemical sensing: development of Ru(ii) half sandwich complex as isoniazid and rifampicin dual sensor.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Homogenous electrochemical sensing using unmodified electrodes remove electrode fabrication challenges and prove effective for detecting sensitive bio-analytes without chances of surface degradation. This work envisages design and optimization of a ruthenium(ii) half-sandwich complex as supradecorated homogeneous electrochemical sensor for simultaneous detection of rifampicin (RIF) and isoniazid (INH) as first-line anti-tuberculosis drugs in aqueous environments. The electrochemical profile of GCE/ruthenium(ii) half-sandwich complex sensor was analyzed using cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy (EIS). The results indicate significant electrochemical parameters corroborating enhanced sensing propensity of GCE/ruthenium(ii) half-sandwich complex over bare GCE for simultaneous estimation of RIF and INH binary mixture. The RIF and INZ analytical figure of merit has been corroborated with their relative supra interactional propensity. Supra interactional propensity has also been predicted to be the plausible mechanism of RIF and INZ electrochemical sensing. Under optimized conditions GCE/ruthenium(ii) half-sandwich complex sensor depicted INH detection limits of 1.2 μM, and RIF detection limit of 32 nM. The comparative study of RIF and INZ analytes individually depicted high sensitivity of 24.57 μA μM
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.