Evidence map›Paper›PMID 40041158›Full record

ArticleTemperature (Austin, Tex.)2025

Facial cooling improves thermal perceptions and maintains the interleukin-6 response during passive heating: A sex comparison.

Yunuo Su, Emma O'Donnell, Sven P Hoekstra, Christof A Leicht

Abstract read
In one paragraph

Article in Temperature (Austin, Tex.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yunuo SuSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.ORCID https://orcid.org/0009-0002-3874-995X
Emma O'DonnellSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.ORCID https://orcid.org/0000-0002-4037-4213
Sven P HoekstraSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.ORCID https://orcid.org/0000-0003-1597-162X
Christof A LeichtSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.ORCID https://orcid.org/0000-0002-3539-8480

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Passively elevating body temperature can trigger a potentially beneficial acute inflammatory response. However, heat therapy often causes discomfort and negative thermal perceptions, particularly in females who generally have lower heat tolerance than males. This study aimed to evaluate the impact of facial cooling on thermal comfort and interleukin-6 concentration in response to 60 minutes of dry heat exposure, and to investigate sex differences in physiological responses and perceptions. 22 healthy young adults (10 females, 12 males; age: 24.4 ± 3.3 years) completed three trials in randomized order using a dry sauna device: 1) Hyperthermia (71.1 ± 1.9°C; HEAT), 2) Hyperthermia with facial cooling via fans (71.1 ± 3.0°C; FAN), and 3) Normothermia (27.0 ± 0.9°C; CON). Blood samples to determine interleukin-6 (IL-6) plasma concentration were collected before and after exposure; basic affect and thermal comfort, rectal and skin temperature were assessed throughout the intervention. Rectal temperature following HEAT (38.0 ± 0.3°C) and FAN (37.8 ± 0.3°C) did not differ between males and females (

Indexed as

inflammationinterleukin-6Passive heatingskin temperaturethermal comfort

Identifiers

PMID40041158
PMCPMC11875509

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.