Evidence map›Paper›PMID 40040995›Full record

ArticleHeliyon2025

Clustering analyses of murine bone marrow-derived neutrophils reveal a phenotypic heterogeneity that can respond differentially to stimulation.

Pedro H Silva, Hernán F Peñaloza, José Cordero, Alexis M Kalergis, Nelson P Barrera, Susan M Bueno

Abstract read
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pedro H SilvaMillennium Institute on Immunology and Immunotherapy, Santiago, 8330025, Chile.
Hernán F PeñalozaMillennium Institute on Immunology and Immunotherapy, Santiago, 8330025, Chile.
José CorderoFacultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile.
Alexis M KalergisMillennium Institute on Immunology and Immunotherapy, Santiago, 8330025, Chile.
Nelson P BarreraFacultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile.
Susan M BuenoMillennium Institute on Immunology and Immunotherapy, Santiago, 8330025, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils are granulocytic cells produced in the bone marrow from a granulocytic progenitor cell. During infection, the production of chemokines and cytokines induces the recruitment of neutrophils to the infected tissue to promote the clearance of microbial pathogens. Several studies have shown that different subpopulations of neutrophils can be identified during infection. However, no previous studies evaluated subpopulations of neutrophils purified from the bone marrow (BM), which are typically used to study the biology of these cells based on the assumption that the neutrophil population is homogeneous. In the present study, responses of purified BM-derived neutrophils to various stimuli such as PMA, LPS, and

Identifiers

PMID40040995
PMCPMC11876930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.