Evidence map›Paper›PMID 40040991›Full record

ReviewHeliyon2025

Therapeutic potential of microalgae-derived natural compounds in diabetic wound healing: A comprehensive review.

Jinjin Pei, Simab Kanwal, Ramachandran Sivaramakrishnan, Kasinee Katelakha

Abstract readReview
In one paragraph

Review in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Polysaccharide based biomaterials for advanced wound healing applications.Frontiers in cellular and infection microbiology · 2026
    Review
  4. Article
  5. Marine drugs · 2025
    Article
  6. Review
  7. Review
  8. Enhanced wound healing through hydrogel:Iranian journal of basic medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jinjin PeiQinba State Key Laboratory of Biological Resources and Ecological Environment, 2011 QinLing-Bashan Mountains Bioresources Comprehensive Development C. I. C., Shaanxi Province Key Laboratory of Bio-Resources, College of Bioscience and Bioengineering, Shaanxi University of Technology, Hanzhong, 723001, China.
Simab KanwalInstitute of Nutrition, Mahidol University, Salaya, Phutthamonthon, Nakhon Pathom, 73170, Thailand.
Ramachandran SivaramakrishnanLaboratory of Cyanobacterial Biotechnology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Kasinee KatelakhaThe Halal Science Center, Chulalongkorn University, Bangkok, 10330, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A variety of cell types and chemical systems are known to interact throughout the complex process of wound healing. In addition to being very uncomfortable for patients, wounds that do not heal properly or become chronic can place a heavy burden on society. The creation of novel treatment approaches can expedite the healing process, reduce the societal burden, and improve patient outcomes. Due to advancements in the field of biomedical science, microalgae have significant potential for use in diabetic wound healing and other wound healing applications. This review delves into the physiological process of wound healing, the use of microalgae in wound healing, and a detailed explanation of the wound healing roles of various microalgal originated bioactive compounds including alginate, pigments, fatty acids, proteins, polysaccharides, flavonoids and phenols. The study discusses the efficacy of photosynthetic hydrogels in drugs and oxygen delivery to the wounded area that is crucial for promoting a good healing process, as well as highlights the drawbacks and challenges involved in using microalgae for wound healing. Given the current state of the art in utilizing microalgae for wound care, this review provides new perspectives for further research, along with insightful advice and innovative suggestions for academics engaged in this area.

Indexed as

Bioactive compoundsDiabetic wound healingHydrogelsMicroalgaeWound care

Identifiers

PMID40040991
PMCPMC11876918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.