ArticleFrontiers in neurology2025
A multicenter analysis to identify the risk factors for stroke recurrence and mortality within 1 year.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Association Between Triglyceride-Glucose Index and in-Hospital Intensive Care Unit Readmission in Ischemic Stroke Patients: A Retrospective Analysis Based on the MIMIC-IV Database.The Kaohsiung journal of medical sciences · 2026Article
- Real-World Comparative Outcomes of Dual vs. Single Antiplatelet Therapy in Acute Ischemic Stroke: A Retrospective Cohort Analysis.Neurology and therapy · 2026Article
- Application of TOAST criteria, comorbidities and outcomes in patients with ischemic stroke: multicenter collaboration in the Dominican Republic.Frontiers in stroke · 2026Article
- Assessing the effects of antidepressant use on stroke recurrence and related outcomes in ischemic stroke patients: a propensity score matched analysis.Frontiers in pharmacology · 2025Article
- Effects of previous steroid treatment on ischemic stroke outcomes: a propensity score-matched hospital analysis.Frontiers in pharmacology · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
Background: Stroke recurrence is a serious and prevalent complication of ischemic stroke that warrants additional investigation. Methods: A hospital-based retrospective observational study included acute-subacute ischemic stroke adult patients. The primary aim was to determine the risk factors associated with recurrent stroke within 365 days. Additionally, a combined outcome consisting of any stroke recurrence or all-cause mortality within 365 days was considered secondary outcome. Univariate and multivariable Cox proportional-hazards models were used to examine the association of risk factors with stroke recurrence and composite death/stroke recurrence. Results: Of 1,244 patients, 112 (9%) experienced stroke recurrence. The multivariable analysis identified risk factors for stroke recurrence including history of previous stroke (HR = 3.65, 95% CI:2.28-5.99, Conclusion: Key findings include a stroke recurrence rate of 9.96% and a combined death/stroke recurrence rate of 21.83% within 365 days. Multivariable analysis confirmed that history of stroke, receiving tPA, experiencing seizures, and depression were significantly associated with stroke recurrence. Implementing additional preventive measures for individuals in these high-risk categories is essential. Further studies are needed to validate our findings.
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