Evidence map›Paper›PMID 40040907›Full record

ArticleFrontiers in neurology2025

A resting-state fMRI cross-sectional study of cardiorespiratory fitness decline after stroke.

Qingming Qu, Kexu Zhang, Hewei Wang, Jie Zhu, Yingnan Lin, Jie Jia

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Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qingming Qu *Department of Rehabilitation Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.
Kexu Zhang *School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Hewei WangDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Jie ZhuDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Yingnan LinDepartment of General Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Jie JiaDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The present study aimed to investigate alterations in neural activity and reorganization of functional networks within critical brain regions associated with reduced cardiorespiratory fitness (CRF) in stroke patients. By employing resting-state functional magnetic resonance imaging (fMRI), we sought to identify specific brain areas that may be implicated in CRF decline among this patient population. Methods: A total of 22 patients with stroke and 15 healthy subjects matched for age, gender, and body mass index were recruited. Rehabilitation assessments included peak oxygen uptake (VO Results: Patients with stroke exhibited significantly lower VO Conclusion: This study observed that CRF levels were lower in stroke patients compared to those in healthy individuals. Resting fMRI analysis was applied to identify CRF-related brain regions (ipsilesional superior temporal, middle frontal, precentral gyri) and networks in patients with stroke. Clinical trial registration: https://www.chictr.org.cn/showproj.html?proj=151095.

Indexed as

amplitude of low-frequency fluctuationsbrain networkcardiorespiratory fitnessfunctional connectivityresting-state fMRI

Identifiers

PMID40040907
PMCPMC11877007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.