Evidence map›Paper›PMID 40040833›Full record

ArticleExploration (Beijing, China)2025

A pH responsive nanocomposite for combination sonodynamic-immunotherapy with ferroptosis and calcium ion overload via SLC7A11/ACSL4/LPCAT3 pathway.

Xue Bai, Jun Kang, Silong Wei, Yun Wang, Yangsui Liu, Bo Yuan, Qian Lu, Huansong Li, Jun Yan, Xi Yang and 1 more

Abstract read
In one paragraph

Article in Exploration (Beijing, China), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xue BaiSchool of Life Sciences Tianjin University Tianjin China.ORCID https://orcid.org/0009-0002-4103-5501
Jun KangSchool of Life Sciences Tianjin University Tianjin China.
Silong WeiChen Guanxing Dental Clinic Ningbo China.
Yun WangHepatobiliary Pancreatic Center Xuzhou Central Hospital Xuzhou China.
Yangsui LiuHepatobiliary Pancreatic Center Xuzhou Central Hospital Xuzhou China.
Bo YuanHepatobiliary Pancreatic Center Xuzhou Central Hospital Xuzhou China.
Qian LuHepatobiliary Pancreatic Center Xuzhou Central Hospital Xuzhou China.
Huansong LiHepatobiliary Pancreatic Center Xuzhou Central Hospital Xuzhou China.
Jun YanHepatobiliary Pancreatic Center Xuzhou Central Hospital Xuzhou China.
Xi YangDepartment of Oral Maxillofacial-Head and Neck Oncology Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University Shanghai China.
Jin ChangSchool of Life Sciences Tianjin University Tianjin China.ORCID https://orcid.org/0000-0002-6752-8526

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonodynamic therapy offers a non-invasive approach to induce the death of tumor cells. By harnessing ultrasound waves in tandem with sonosensitizers, this method produces reactive oxygen species (ROS) that inflict oxidative damage upon tumor cells, subsequently causing their demise. Ferroptosis is a regulatory form of cell death that differs from other forms, characterized by iron accumulation, ROS accumulation, and lipid peroxidation. In the presented research, a nanoparticle formulation, parthenolide/ICG-CaCO

Indexed as

ferroptosisparthenolidesonodynamic therapytumor immunotherapy

Identifiers

PMID40040833
PMCPMC11875445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.