Evidence map›Paper›PMID 40040761›Full record

ArticleJournal of surgical case reports2025

Multinodular benign goitre as an immediate threat to the airway: a case report.

Andreia J Santos, João Luís Pinheiro, Daniela Gaspar, Aline Gomes, Ana Oliveira, Jorge Pereira

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical characteristics of multinodular goiter causing tracheal compression.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreia J SantosDepartment of General Surgery, Unidade Local de Saúde Viseu Dão-Lafões, Avenida Rei Dom Duarte, 3504-509, Viseu, Portugal.ORCID https://orcid.org/0000-0002-3312-8882
João Luís PinheiroDepartment of General Surgery, Unidade Local de Saúde Viseu Dão-Lafões, Avenida Rei Dom Duarte, 3504-509, Viseu, Portugal.ORCID https://orcid.org/0000-0002-1942-8512
Daniela GasparDepartment of General Surgery, Unidade Local de Saúde Viseu Dão-Lafões, Avenida Rei Dom Duarte, 3504-509, Viseu, Portugal.ORCID https://orcid.org/0000-0003-3789-4653
Aline GomesDepartment of General Surgery, Unidade Local de Saúde Viseu Dão-Lafões, Avenida Rei Dom Duarte, 3504-509, Viseu, Portugal.
Ana OliveiraDepartment of General Surgery, Unidade Local de Saúde Viseu Dão-Lafões, Avenida Rei Dom Duarte, 3504-509, Viseu, Portugal.
Jorge PereiraDepartment of General Surgery, Unidade Local de Saúde Viseu Dão-Lafões, Avenida Rei Dom Duarte, 3504-509, Viseu, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute upper airway obstruction (AUAO) due to benign thyroid disease is a rare but life-threatening condition. We report a case of an 82-year-old woman with a toxic multinodular goitre who presented to the emergency department with confusion and noisy breathing. Despite being initially stable, she developed progressive stridor and hypoxemia. A neck CT revealed significant tracheal compression due to the goitre. Immediate intubation and corticosteroid treatment were followed by urgent total thyroidectomy and tracheostomy. She was admitted to the ICU for management of laryngeal oedema and rehabilitation. The pathophysiology of AUAO in benign goitres is multifactorial, involving potential haemorrhage, infection, or exacerbation of comorbid respiratory conditions. Early diagnosis through imaging and prompt intervention with thyroidectomy is crucial for survival. Postoperative monitoring for complications like laryngeal oedema and tracheomalacia is essential. This case emphasizes the need for vigilance in managing airway compromise in patients with large multinodular goitres.

Indexed as

acute upper airway obstructionemergency surgerylaryngeal oedemamultinodular goitrethyroidectomytracheal compression

Identifiers

PMID40040761
PMCPMC11879074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.