Evidence map›Paper›PMID 40040533›Full record

SynthesisThe Gerontologist2025

The Impact of Multidisciplinary Transitional Care Interventions for Complex Care Needs: A Systematic Review and Meta-Analysis.

Romain Collet, Juul van Grootel, Johanna van Dongen, Suzanne Wiertsema, Raymond Ostelo, Marike van der Schaaf, Elena Lazzari, Edwin Geleijn, Mel Major, Marike van der Leeden

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The Gerontologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. TRANSFER-I: Hospitalised Older Adults and Their Carers' Perspectives of the Transition Home: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Romain ColletFaculty of Science, Department of Health Sciences, Vrije University Amsterdam, Amsterdam Movement Sciences Research Institute, Musculoskeletal Health, Amsterdam, The Netherlands.ORCID 0000-0002-4621-4077
Juul van GrootelAmsterdam Movement Sciences, Ageing, and Vitality, Amsterdam, The Netherlands.
Johanna van DongenFaculty of Science, Department of Health Sciences, Vrije University Amsterdam, Amsterdam Movement Sciences Research Institute, Musculoskeletal Health, Amsterdam, The Netherlands.
Suzanne WiertsemaDepartment of Rehabilitation Medicine, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Raymond OsteloFaculty of Science, Department of Health Sciences, Vrije University Amsterdam, Amsterdam Movement Sciences Research Institute, Musculoskeletal Health, Amsterdam, The Netherlands.
Marike van der SchaafAmsterdam Movement Sciences, Ageing, and Vitality, Amsterdam, The Netherlands.
Elena LazzariFaculty of Behavioural and Movement Sciences, Department of Human Movement Sciences, Vrije University Amsterdam, Amsterdam, The Netherlands.
Edwin GeleijnDepartment of Rehabilitation Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Mel MajorFaculty of Health, Department of Physical Therapy, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
Marike van der LeedenAmsterdam Movement Sciences, Ageing, and Vitality, Amsterdam, The Netherlands.

Funding

ZonMw 10270022110004ZonMw 10270022110008
6 · The paper itself

Abstract

BACKGROUND AND

objectivesMultidisciplinary transitional care interventions (MTCIs) ensure care coordination and continuity after hospital discharge while addressing (older) patients' complex care needs related to their physical, nutritional, cognitive, and/or psychological status. This study aimed to identify, critically appraise, and synthesize the current body of evidence investigating the effectiveness of such interventions. RESEARCH DESIGN AND

methodsMedline, Embase, CINAHL, and CENTRAL were searched for randomized controlled trials assessing MTCIs' impact on readmissions, mortality, and health-related outcomes from inception to July 2024. Risk of bias was evaluated with the Risk of Bias-2 tool. Subgroup analyses assessed whether different intervention types affected outcomes differently. The certainty of the evidence was assessed with the Grading of Recommendations Assessment, Development, and Evaluation approach and the credibility of subgroup analyses with the Instrument to evaluate the Credibility of Effect Modification Analyses.

resultsForty-nine trials involving 25,566 patients were included. There was low certainty that MTCIs reduced readmissions (relative risk [RR] = 0.88; 95% confidence intervals [95% CI] = 0.80 to 0.96) and high certainty for reduced mortality (RR = 0.92; 95% CI = 0.84 to 1.01). There was low to moderate certainty that MTCIs improved physical quality of life (standardized mean difference [SMD] = 0.54; 95% CI = -0.06 to 1.15), mental quality of life (SMD = 0.44; 95% CI = -0.08 to 0.96), patient satisfaction (SMD = 0.49; 95% CI = -0.14 to 1.12), and physical performance (SMD = 0.49; 95% CI = -0.11 to 1.10). Subgroup analysis revealed a larger and statistically significant effect on physical performance in more complex interventions (SMD = 0.83; 95% CI = 0.02 to 1.65). DISCUSSION AND IMPLICATIONS: These findings suggest that MTCIs can reduce readmissions and mortality while improving quality of life and physical performance. Further investigations should focus on tailoring MTCIs to specific contexts to maximize their impact.

Indexed as

Patient Care TeamTransitional CareAgedHumansPatient DischargePatient ReadmissionQuality of LifeRandomized Controlled Trials as TopicContinuity of patient careMeta-analysisMultimorbidityQuality of lifeTransitional care

Identifiers

PMID40040533
PMCPMC12086065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.