Evidence map›Paper›PMID 40040269›Full record

ArticlePhysiological reports2025

Baseline arterial stiffness does not influence post-exercise reduction in pulse wave velocity.

Natalia S Lima, Ronald E Jackson, Sara R Sherman, Brooks A Hibner, Bo Fernhall, Tracy Baynard, Craig Crandall, Shane A Phillips, Philip S Clifford

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natalia S LimaIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.
Ronald E JacksonIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.
Sara R ShermanIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-3456-5213
Brooks A HibnerIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-2830-4482
Bo FernhallIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.
Tracy BaynardIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.
Craig CrandallDepartment of Internal Medicine, University of Texas Southwestern, Dallas, Texas, USA.ORCID https://orcid.org/0000-0001-7792-9713
Shane A PhillipsIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.
Philip S CliffordIntegrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-1849-3969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We manipulated baseline peripheral arterial stiffness via changes in local arterial pressure with different limb positions to test the hypothesis that the magnitude of decrease in arterial stiffness post exercise/compression would be less when baseline stiffness is higher with the arm below the heart. Brachial-radial pulse wave velocity (PWV) was measured with tonometers in 19 healthy volunteers before and after 5 min of rhythmic handgrip exercise or passive forearm compressions with the arm positioned below or above the heart. Brachial-radial PWV was reduced 5 min after handgrip exercise below (10.4 ± 2.6 to 8.7 ± 2.2 m/s) and above (6.4 ± 1.3 to 5.3 ± 1.0 m/s) the heart, with no difference between positions (p > 0.05). PWV was also reduced 5 min after passive compressions with the arm below (10.8 ± 2.0 to 9.8 ± 2.1 m/s) and above (7.5 ± 1.4 to 5.7 ± 1.1 m/s), with no difference between positions (p > 0.05). Changes in local arterial pressure associated with arm position resulted in differences in baseline PWV but did not affect the magnitude of reduction in PWV with exercise or compressions. Reductions in peripheral arterial stiffness observed after rhythmic handgrip exercise and passive compressions were independent of baseline arterial stiffness.

Indexed as

ExerciseVascular StiffnessAdultBlood PressureBrachial ArteryFemaleForearmHand StrengthHumansMalePulse Wave AnalysisYoung Adultblood flowcompressionlocal arterial pressurepulse wave velocity

Identifiers

PMID40040269
PMCPMC11880123

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.