Evidence map›Paper›PMID 40038840›Full record

ArticleGeneral thoracic and cardiovascular surgery cases2025

Mitral valve repair in severe mitral regurgitation due to Barlow's disease with concomitant mitral annular disjunction: a case report.

Koji Furukawa, Ayaka Iwasaki, Hirohito Ishii, Sakaguchi Shuhei, Kousuke Mori, Shohei Hiromatsu

Abstract read
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Article in General thoracic and cardiovascular surgery cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

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2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Koji FurukawaDivision of Cardiovascular Surgery, Department of Surgery, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki City, Miyazaki, 889-1692, Japan. koji_furukawa@med.miyazaki-u.ac.jp.ORCID http://orcid.org/0000-0002-5264-9659
Ayaka IwasakiDivision of Cardiovascular Surgery, Department of Surgery, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki City, Miyazaki, 889-1692, Japan.
Hirohito IshiiDivision of Cardiovascular Surgery, Department of Surgery, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki City, Miyazaki, 889-1692, Japan.
Sakaguchi ShuheiDivision of Cardiovascular Surgery, Department of Surgery, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki City, Miyazaki, 889-1692, Japan.
Kousuke MoriDivision of Cardiovascular Surgery, Department of Surgery, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki City, Miyazaki, 889-1692, Japan.
Shohei HiromatsuDivision of Cardiovascular Surgery, Department of Surgery, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki City, Miyazaki, 889-1692, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMitral annular disjunction (MAD) is characterized by the detachment of the mitral valve-left atrial junction from the left ventricular myocardium. The association of MAD with Barlow's disease and its relevance to treatment are increasingly recognized. CASE PRESENTATION: A 75-year-old male with a history of mitral regurgitation (MR) and ablation for paroxysmal atrial fibrillation was diagnosed with severe MR due to Barlow's disease, as confirmed by echocardiography. Imaging revealed disjunction at the mitral valve's posterior annulus. During surgery, the posterior leaflet was resected along the annulus with precise height adjustments. A 6-mm separation between the mitral valve-left atrial junction and the left ventricular myocardium was sutured using a four-stitch mattress technique. The procedure included leaflet repair, insertion of artificial chordae, and mitral annuloplasty. Postoperatively, the MAD was corrected successfully, eliminating the severe MR.

conclusionsConfirming the presence of MAD before surgery is essential for patients with MR. Surgical correction of MAD is imperative when present to address the disjunction effectively.

Indexed as

Barlow’s diseaseMitral annular disjunctionMitral regurgitationMitral valve repair

Identifiers

PMID40038840
PMCPMC11881260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.