Evidence map›Paper›PMID 40038779›Full record

ArticleBJU international2025

Pelvic organ-sparing robot-assisted radical cystectomy in women with bladder cancer.

Juhana Rautiola, Johan Björklund, Reuben Ben-David, Viktor Skokic, Giovanni Cacciamani, Mihir Desai, Linda Dey, Reza Mehrazin, Gus Miranda, John Sfakianos and 2 more

Abstract readMulticenter Study
In one paragraph

Article in BJU international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juhana RautiolaDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0008-7208-6321
Johan BjörklundDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-3254-3993
Reuben Ben-DavidDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID https://orcid.org/0000-0001-7946-7145
Viktor SkokicDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Giovanni CacciamaniCatherine & Joseph Aresty Department of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Mihir DesaiCatherine & Joseph Aresty Department of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-3744-8234
Linda DeyDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Reza MehrazinDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gus MirandaCatherine & Joseph Aresty Department of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.
John SfakianosDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Neeraja TilluDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID https://orcid.org/0000-0002-4149-0486
Peter WiklundDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the oncological and complication outcomes in women who have undergone pelvic organ-sparing robot-assisted radical cystectomy (RARC). PATIENTS AND

methodsWe conducted a retrospective, multicentre cohort study of women with bladder cancer undergoing RARC with intracorporeal urinary diversion. The primary outcomes were overall survival (OS) and cancer-specific survival (CSS), and secondary outcomes were 30- and 90-day high-grade complications in patients undergoing organ-sparing RARC vs non-organ-sparing RARC. Kaplan-Meier analyses, the log-rank test and Cox proportional hazard models were used to assess the associations of pelvic organ-sparing RARC with both OS and CSS. The Mann-Whitney test and chi-squared and Fisher's tests were used to compare continuous and categorical variables, respectively.

resultsA total of 269 women underwent RARC, of whom 81 underwent pelvic organ-sparing RARC. There was no statistically significant difference between the groups in terms of clinical or pathological T stage, and the recurrence rates were similar in the two groups. There were no significant differences in CSS or OS between the groups. The two groups had similar complication profiles and rates. The incidence of high-grade (Clavien-Dindo grade ≥3a) complications was similar in the two groups: organ-sparing vs non-organ-sparing RARC: 13% vs 14% for early complications (P = 0.87) and 7% vs 6% (P = 0.70) for late complications.

conclusionsWomen with bladder cancer who underwent pelvic organ-sparing RARC and intracorporeal urinary diversion had similar oncological and complication outcomes compared to those who underwent non-organ-sparing RARC. Pelvic organ-sparing RARC could be considered in well selected women with bladder cancer, resulting in improved quality of life and functional outcomes.

Indexed as

CystectomyOrgan Sparing TreatmentsRobotic Surgical ProceduresUrinary Bladder NeoplasmsAgedFemaleHumansMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeUrinary Diversionbladder cancercomplicationsfemale cystectomyoutcomespelvic organ‐sparing cystectomyrobot‐assisted radical cystectomy

Identifiers

PMID40038779
PMCPMC12415325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.