Evidence map›Paper›PMID 40038715›Full record

Trial reportBMC oral health2025

Efficiency of different treatment modalities on radiation induced trismus for maxillofacial cases: a parallel randomized clinical trial.

Marwa Ahmed Aboelez, Abdallah Mohammed Ibrahim, Mohammed A ElSawy, Nermeen El Sayed El-Khamisy

2 registry-linked trialsAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06413628 nacompletednot on this map

Efficiency of Different Treatment Modalities on Radiation Induced Trismus for Maxillofacial Cases

TypeinterventionalSponsorMansoura UniversityRan2022 to 2023Enrolled36ConditionsTrismus, CancerArmsscrew tapered appliance
NCT07079384 naactive not recruitingnot on this map

Evaluation of Patient Comfort and Satisfaction After the Construction of Maxillary Obturator Prosthesis for Limited Mouth Opening in Maxillofacial Cases With Different Approaches: Cross Over Randomized Clinical Trial

TypeinterventionalSponsorMansoura UniversityRan2025 to 2025Enrolled30ConditionsPatient Satisfaction, MaxilofacialArmsThe patient will be instructed about wearing the prosthesis. First, seat the prosthesis in a posterior undercut, then rotate the prosthesis slightly superiorly in the defect area and engage the anteri
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marwa Ahmed AboelezFaculty of Dentistry, Department of Prosthodontics, Mansoura University, 1 El Haramine St. from Talkha, Mansoura, Egypt. marwa_dental_2010@yahoo.com.
Abdallah Mohammed IbrahimFaculty of Dentistry, Department of Prosthodontics, Mansoura University, 1 El Haramine St. from Talkha, Mansoura, Egypt.
Mohammed A ElSawyDepartment of Prosthodontics, Menoufia University, Shibin Al Kawm, Egypt.
Nermeen El Sayed El-KhamisyFaculty of Dentistry, Department of Prosthodontics, Mansoura University, 1 El Haramine St. from Talkha, Mansoura, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor more than 80% of patients with head and neck cancer, radiation therapy (RT) is a crucial component of their treatment plane which causes impairment for the masticatory apparatus functions leading to trismus. The study objective was to compare the efficacy of different treatment modalities for patients with RT-induced trismus on maximum mouth opening (MMO), visual analogue scale (VAS) (primary outcomes) patient satisfaction (secondary outcome).

methodsThirty-six patients with trismus after radiation therapy were classified equally and randomly into three groups (n = 12 per group): Group A was given threaded tapered screw appliance therapy (TTSA), Group B was given low-level laser therapy (LLLT), and Group C was given both threaded tapered screw appliance and low-level laser therapy (LLLT + TTSA). Maximum mouth opening (MMO), visual analogue scale (VAS) and Gothenburg Trismus Questionnaire (GTQ) scores and time required to achieve normal state were evaluated at baseline, 1, 2, 4 weeks, 3 and 6 months after the intervention. Data were collected and analysed using SPSS software.

resultsRegarding VAS and MMO, there was a statistically significant difference at different times of evaluation within all groups where (P <.0001). Regarding GTQ, group C recorded the least values for GTQ symptoms followed by group B followed by group A. Between groups A, B, and C at six months, there was a statistically significant difference for VAS. At three and six months, there was a statistically significant difference between all groups for MMO. At three and six months, there was a statistically significant difference between groups for all GTQ domains.

conclusionAll available therapy modalities have the potential to effectively improve radiation induced trismus; however, the combination of TTSA and LLLT group appears to yield the most rapid and optimal enhancement. CLINICAL TRIAL REGISTRY NUMBER: (NCT06413628) (05/12/2024) Retrospectively registered.

Indexed as

Head and Neck NeoplasmsLow-Level Light TherapyTrismusAdultAgedFemaleHumansMaleMiddle AgedPatient SatisfactionTreatment OutcomeLow-level laserRadiation therapyThreaded tapered screw applianceTrismus

Identifiers

PMID40038715
PMCPMC11877843

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.