Evidence map›Paper›PMID 40038708›Full record

ReviewVirology journal2025

Unique skin nodules following COVID-19 vaccination: a case report of cutaneous plasmacytosis and review of the literature.

Xiaoxi Xu, Wuwu Ding, Haizhen Song, Dong Wang

Abstract readCase ReportsReview
In one paragraph

Review in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoxi Xu *Department of Dermatovenereology, Deyang People's Hospital, NO.173, Taishan North Road, Jingyang District, Deyang, Sichuan, 618000, China. 410127242@qq.com.ORCID 0000-0001-6891-0199
Wuwu Ding *Department of Pathology, Deyang People's Hospital, Deyang, China.ORCID 0009-0003-9124-0447
Haizhen SongDepartment of Dermatovenereology, Deyang People's Hospital, NO.173, Taishan North Road, Jingyang District, Deyang, Sichuan, 618000, China.ORCID 0009-0001-0994-8856
Dong WangDepartment of Dermatovenereology, Deyang People's Hospital, NO.173, Taishan North Road, Jingyang District, Deyang, Sichuan, 618000, China.ORCID 0009-0006-3120-8690

Funding

Science and Technology Project of Sichuan Provincial Health Commission 24WSXT025
6 · The paper itself

Abstract

backgroundCutaneous plasmacytosis (CP) is a rare disorder that may affect two or more organ systems, such as skin, lymph nodes or lungs. The pathogenesis of CP remains unknown, and in most cases, the condition follows a chronic and benign clinical course without spontaneous remission. CASE PRESENTATION: A 50-year-old male who developed necrotizing skin nodules without other systemic abnormalities four days after the first doses of the Coronavirus disease 2019 (COVID-19) vaccination. Oral prednisone improved the lesions by approximately 70%. However, signs of CP recurrence manifested 15 days after the second dose of COVID-19 vaccination. Ultimately, the patient experienced spontaneous remission after contracting SARS-CoV-2 infection.

conclusionThis case uniquely associates COVID-19 inactivated vaccine with CP, where the same lesions appeared after two vaccinations and subsequently resolved following SARS-CoV-2 infection. This provides valuable clinical data for future studies on viral infections and cutaneous B-cell immunity.

Indexed as

COVID-19COVID-19 VaccinesPlasma CellsSkinSkin DiseasesHumansMaleMiddle AgedPrednisoneSARS-CoV-2VaccinationCOVID-19 VaccinesPrednisoneCOVID-19 vaccineCutaneous immunityCutaneous plasmacytosisIL-6Immune toleranceSkin adverse reactions

Identifiers

PMID40038708
PMCPMC11877820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.