Evidence map›Paper›PMID 40038672›Full record

ArticleBMC pediatrics2025

Meconium aspiration syndrome and associated factors among neonates admitted at neonatal intensive care unit at Northwest Ethiopia comprehensive specialized hospitals Northwest Ethiopia 2023.

Marta Adugna, Kibret Asmare, Amare Wondim

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Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Marta AdugnaDepartment of neonatal health nursing, school of nursing, University of Gondar, Gondar, Ethiopia. martaadugna21@gmail.com.
Kibret AsmareDepartment of surgical nursing, school of nursing, University of Gondar, Gondar, Ethiopia.
Amare WondimDepartment of pediatrics and child health nursing, school of nursing, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMeconium aspiration syndrome is a life-threatening respiratory disease due to the aspiration of meconium-stained amniotic fluid into the lungs, resulting in neonatal morbidity and mortality. Impacts of meconium aspiration syndrome include respiratory failure, intellectual disability, persistent pulmonary hypertension, and air leaks. But there is a paucity of literature in Ethiopia, especially in the study area regarding the study topic. The aim of this study is to assess the proportion of meconium aspiration syndrome and associated factors among neonates admitted at the neonatal intensive care unit in North West Comprehensive Specialized Hospital, Northwest Ethiopia, 2023.

methods-An institutional-based cross-sectional study was conducted among 414mothers-neonate pairs from April 15-May 15/2023. Systematic random sampling was used to obtain study participants. Maternal interviews and a review of neonatal charts were used to gather data from 414 respondents. Then the collected data was entered and coded into EPi-Data version 4.6.0.2 and exported to STATA version 14 for analysis. Both the bi-variable and multi-variable logistic regression models were used for analysis. AOR and 95% CI were used to measure association and strength, with statistical significance assessed at a p-value < 0.05.

results- A total of 414 neonate-mother pairs were involved with a 98% response rate. The overall prevalence of meconium aspiration syndrome was 23.43% with a 95% CI (19.6-27.8). Gestational age ≥ 41 wks (AOR = 4.8, CI = 2.02-11.22), labor duration ≥ 12 h (AOR = 2, 95%CI = 1.10-3.84), Premature Rupture of Membrane (AOR = 4.6, 95%CI = 1.12-10.12), oligohydramnios (AOR = 4.2, 95%CI, 2.17-8.14) and breech presentation (AOR = 6.9, 95%CI = 2.169-8.13) were significantly associated with meconium aspiration syndrome. CONCLUSION AND RECOMMENDATION: The prevalence of meconium aspiration syndrome was relatively high. And Postterm gestation, oligohydramnios, duration of labor, Premature Rupture of Membrane, and breech presentation increased the prevalence of meconium aspiration syndrome. Therefore, to reduce the risk of meconium aspiration syndrome, Health professionals should assess laboring women for the presence of these factors and should stay alert to detect MSAF early for better fetal and maternal health outcomes.

Indexed as

Intensive Care Units, NeonatalMeconium Aspiration SyndromeAdultCross-Sectional StudiesEthiopiaFemaleHospitals, SpecialHumansInfant, NewbornLogistic ModelsMalePregnancyPrevalenceRisk FactorsYoung AdultEthiopiaMeconium aspiration syndromeNeonatesPrevalence

Identifiers

PMID40038672
PMCPMC11881333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.