ArticleBMC public health2025
Trends and outcomes of heart failure hospitalizations during COVID-19 pandemic.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Mortality Trends in the United States due to Concurrent Heart Failure, Atrial Fibrillation/Flutter, and Sepsis.medRxiv : the preprint server for health sciences · 2026Article
- Trends in heart failure prevalence in post-disaster Fukushima residents 2015-2021.Scientific reports · 2026Article
- Mortality Trends in the United States due to Concurrent Heart Failure, Atrial Fibrillation/Flutter and Sepsis.Cardiology and cardiovascular medicine · 2026Article
- Cardiovascular Complications of COVID-19 Disease: A Narrative Review.Diseases (Basel, Switzerland) · 2025Review
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOVID-19 has affected many hospitalizations. In this study, we intended to understand the effects of COVID-19 pandemic on heart failure hospitalizations in the state of California.
methodThis study was a retrospective analysis of California State Inpatient Database during March to December of 2019 and 2020. Adult hospitalizations with heart failure were included for the analysis. Main outcome variables were in-hospital mortality, mechanical ventilation, mechanical circulatory support, vasopressor use, and acute respiratory distress syndrome (ARDS).
resultsThere were 450,771 (53.7%) heart failure hospitalizations during March to December of 2019, compared to 388,795 (46.3%) during March to December of 2020 (relative decrease, 13.7%). Heart failure hospitalization rates were lower during 2020, compared to 2019. Comparison of adverse hospital outcomes across the two-time frames showed that in-hospital mortality (2.9% versus 2.7%, P = 0.003), mechanical circulatory support (0.7% versus 0.5%. P < 0.001), vasopressor use (1.3% versus 1.0%, P < 0.001), and ARDS (0.1% versus 0.06%, P = 0.007) were significantly higher among hospitalizations in 2020. Regression analysis showed that the odds of in-hospital mortality (OR, 1.09; 95% CI, 1.06-1.11), mechanical ventilation (OR, 1.07; 95% CI, 1.05-1.09), vasopressor use (OR, 1.07; 95% CI, 1.04-1.10), and ARDS (OR, 1.74; 95% CI, 1.58-1.91) were significantly higher among heart failure hospitalizations in 2020.
conclusionsOur study found that patients with heart failure hospitalized during the COVID-19 pandemic had greater in-hospital adverse events such as greater in-hospital mortality, mechanical ventilation use, vasopressor use, and ARDS. These findings warrant that heart failure required prompt hospitalization and treatment irrespective of restrictive mandates during COVID-19 pandemic.
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