Evidence map›Paper›PMID 40038604›Full record

ArticleBMC genomics2025

Whole genome insights into genetic diversity, introgression, and adaptation of Yunnan indigenous cattle of Southwestern China.

Xiwen Guan, Weixuan Xiang, Kaixing Qu, Zulfiqar Ahmed, Jianyong Liu, Ming Cai, Jicai Zhang, Ningbo Chen, Chuzhao Lei, Bizhi Huang

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In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

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0cells of the map it votes in
9citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Xiwen GuanYunnan Academy of Grassland and Animal Science, Kunming, China.
Weixuan XiangKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Kaixing QuChuxiong Normal University, Chuxiong, China.
Zulfiqar AhmedDepartment of Livestock and Poultry Production, Faculty of Veterinary and Animal Sciences, University of Poonch Rawalakot, Azad Jammu and Kashmir, Pakistan.
Jianyong LiuYunnan Academy of Grassland and Animal Science, Kunming, China.
Ming CaiYunnan Academy of Grassland and Animal Science, Kunming, China.
Jicai ZhangYunnan Academy of Grassland and Animal Science, Kunming, China.
Ningbo ChenKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Chuzhao LeiKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China. leichuzhao1118@126.com.
Bizhi HuangYunnan Academy of Grassland and Animal Science, Kunming, China. hbz@ynbp.cn.

Funding

Chuxiong Science and Technology Leading Talents CXKJLJRC2023-07the China Agriculture Research System of MOF and MARA CARS-37the Construction of Yunling Cattle Technology Innovation Center and Industrialization of Achievements 2019ZG007the Program of Yunling Scholar and Yunling Cattle Special Program of Yunnan Joint Laboratory of Seeds and Seeding Industry 202205AR070001Yunnan Expert Workstations 202305AF150156
6 · The paper itself

Abstract

backgroundYunnan Province, located in Southwestern China, the intricate geography, variable climate, and abundant vegetation of the region have collectively contributed to shaping the distinctive germplasm characteristics observed in Yunnan indigenous cattle through prolonged domestication. The different breeds of Yunnan cattle exhibit distinct advantageous characteristics and traits, which are an important source of genetic variation because they might carry alleles that enable them to adapt to local environment and tough feeding conditions. However, a comprehensive genomic landscape of genetic resources has yet to be delineated.

resultsHerein, we employed 140 whole-genome sequencing data from Yunnan indigenous cattle across eight breeds to elucidate their genetic diversity and population structure. Utilizing both uniparental and biparental markers, we elucidated the intricate genetic composition of Yunnan indigenous cattle, which is closely correlated with the geographic environment. A predominant East Asian indicine ancestry which gradually diminishes towards the north. The analysis revealed a high genetic diversity among populations and a low-to-moderate inbreeding coefficient, underscoring the rich genetic reservoir of Yunnan cattle breeds. Additionally, gene flow between Yunnan indicine and wild Bos species in and around Yunnan was verified, highlighting localized introgression from Yunnan Gayal as a critical factor in the successful adaptation of Yunnan indicine cattle to the local hot and humid environments.

conclusionsOur findings established the SNPs database for facilitating resource conservation and selective breeding. Moreover, these valuable insights into the genomic diversity and adaptive history of Yunnan indigenous cattle breeds contribute significantly to our understanding of their evolutionary dynamics and offer a foundation for future genetic improvement and conservation strategies.

Indexed as

Adaptation, PhysiologicalGenetic IntrogressionGenetic VariationGenomicsAnimalsBreedingCattleChinaGene FlowGenetics, PopulationPolymorphism, Single NucleotideWhole Genome SequencingAdaptationIntrogressionWhole-genome sequencingYunnan cattle

Identifiers

PMID40038604
PMCPMC11881512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.