ArticleBMC infectious diseases2025
A combined model based on lung CT imaging and clinical characteristics for the diagnosis of AIDS with infection of Talaromyces marneffei.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Article
- Machine learning-based high-specificity diagnostic model forFrontiers in microbiology · 2025Article
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8 authors.
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Abstract
objectiveTo construct a combined model based on the CT and clinical characteristics of acquired immune deficiency syndrome (AIDS) with infection of Talaromyces marneffei (TM) and evaluate the diagnostic efficacy of the combined model.
methodsA retrospective analysis was conducted on 225 patients with AIDS patients with pulmonary infection admitted to the Shanghai Public Health Clinical Center from February 2012 to October 2022. Based on the final microbiological test results, they were divided into a group infected with TM and a group not infected with TM. Univariate and multivariate analyses were conducted on the lung CT imaging and clinical characteristics of these 225 patients. A nomogram was used to construct a combined model, and a calibration plot was drawn to test the diagnostic efficacy of the combined model.
resultsMultivariate logistic regression analysis showed that fever, rash, elevated PLT, elevated Hb, CD4
conclusionThe combined model constructed in this study has certain clinical value for evaluating whether AIDS co-infection is caused by TM. CLINICAL TRIAL: Not applicable.
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