Evidence map›Paper›PMID 40038362›Full record

ArticleScientific reports2025

Effects of drinking slightly acidic electrolyzed water on the growth health, blood physiology, and intestinal development in mice.

Zhifang Shi, Lei Xi, ShuiLin Gao, ZhengYang Shi, XiaoTong Wang, Zhangying Ye, Pu Cheng

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhifang ShiCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China.
Lei XiCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China. xilei@hnuahe.edu.cn.
ShuiLin GaoCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China.
ZhengYang ShiCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China.
XiaoTong WangCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China.
Zhangying YeCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, China.
Pu ChengCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China.

Funding

the China Scholarship Council 202008410327the Doctoral Research Foundation of Henan University of Animal Husbandry and Economy 2021HNUAHEDF001
6 · The paper itself

Abstract

Slightly acidic electrolyzed water (SAEW) as a disinfectant might be ingested by humans and animals along with food and drinking water. The present study explored whether adding SAEW to drinking water affects the drinking water intake, food intake, body weight, intestinal morphology, digestive enzyme activity, and antioxidant enzyme activity of mice. This will provide a theoretical basis for the biosafety of SAEW as a food and drinking water disinfectant. The present study selected and randomly divided 96 4-week-old Kunming mice into three groups: control, 0.5 mg/L SAEW, and 5.0 mg/L SAEW groups. The experiment lasted 60 days. The present study showed that drinking SAEW had no noticeable effect on the food intake, water intake, body weight, and blood biochemical indexes of mice. SAEW significantly increased the plasma superoxide dismutase inhibition rate, glutathione content, and total antioxidant capacity of mice (p < 0.05). The fructose-6-phosphate kinase, isocitrate dehydrogenase, and malate dehydrogenase activities of mice in the SAEW group were significantly increased. Furthermore, SAEW promoted the morphological development of the small intestine and increased the activities of amylase, lipase, and protease. Therefore, the 0.5 and 5.0 mg/L SAEW was beneficial for mice, and improved the body's antioxidative, glucose-metabolizing, and digestive ability.

Indexed as

Drinking WaterIntestinesAnimalsAnimals, Outbred StrainsAntioxidantsBody WeightEatingElectrolysisMaleMiceAntioxidantsDrinking WaterAntioxidant capacityDigestiveHealthMetabolize glucoseMiceSlightly acidic electrolyzed water

Identifiers

PMID40038362
PMCPMC11880203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.