Evidence map›Paper›PMID 40038347›Full record

ArticleScientific reports2025

Prevalence and impact of fertility preservation among young women with breast cancer.

Min Chen, Xuan Wang, Ning Lan, YanKe Chen, Ying Gao, Junyang Wang, WenJuan Wang, Min Jiao, Shuheng Bai, Wenyang Li and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The experience of fertility preservation decision-making in hematopoietic stem cell transplantation patients: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Review
  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Min ChenDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Xuan WangDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Ning LanDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
YanKe ChenSchool of Basic Medical Sciences of Xi'an Jiaotong University, Xi'an, 710061, China.
Ying GaoDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Junyang WangSchool of Basic Medical Sciences of Xi'an Jiaotong University, Xi'an, 710061, China.
WenJuan WangDepartment of Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Min JiaoDepartment of Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Shuheng BaiDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Wenyang LiDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Fang WuDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Fengyuan HuDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Yong ZhangDepartment of Surgical Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China. yongzhang761@mail.xitu.edu.cn.
Juan RenDepartment of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China. 869491533@qq.com.

Funding

Scientific and Technological Research Foundation of Shaan'xi Province, Key Research and Development Project, General project JR, 2023-YBSF-666the Basic and Clinical Integration Innovation Project of Xi' an Jiao tong University JR,YXJLRH2022006 YG, YXJLRH 2022004the Nanjing Tianqing Scientific Research Fund of First Affliated Hospital of Xi'an Jiaotong University JR, TQ202205the Shaanxi Provincial Key Research and Development Plan Project (Key support projects Category A) JR, 2021A011
6 · The paper itself

Abstract

To observe the current situation of fertility preservation among female breast cancer patients ≤ 40 years old and analyze the related factors which influence the utilization of fertility preservation. A single-center retrospective questionnaire was conducted investigating patients diagnosed with breast cancer attending The First Affiliated Hospital of Xian JiaoTong University between January 2016 and December 2019. The questionnaire was redesigned based on previous similar research and the questions needed in this study. Rates of utilization of preservation services were compared based on patients' demographic and economic-social information, disease characteristic information and fertility related information. Univariate and multivariate logistic regression analysis was used to assess the relationship between utilization of fertility preservation and sociodemographic factors, previous reproductive-related problems. 313 patients were successfully interviewed. 60/313patients (19.2%) had utilized fertility preservation. Younger patients (< 30 years of age), patients with 1 or no child, and patients had higher education level were more likely to pursue fertility preservation than their matched counterparts. Age, parity, and education level of breast cancer patients may impact rates of fertility preservation among reproductive age women diagnosed with breast cancer. Thus, further attention to age difference and patient's desire for future fertility could help to improve gaps in fertility preservation. These findings have guidance for counseling young breast cancer patients.

Indexed as

Breast NeoplasmsFertility PreservationAdultAge FactorsFemaleHumansPrevalenceRetrospective StudiesSurveys and QuestionnairesYoung AdultBreast cancerFertility preservation

Identifiers

PMID40038347
PMCPMC11880200

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.