ArticleNature communications2025
A framework for integrating genomics, microbial traits, and ecosystem biogeochemistry.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Functional-Taxonomic Scaling Resolves Conflicting Average Genome Size Estimates Across Environmental Gradients.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A Diffusion-Driven CH4-O2 Boundary Structures Methane Oxidation and Carbon Transformation in Upland Soils.Environmental science & technology · 2026Article
- Microbial Functional Gene Abundance-Integrated Modeling of Global Methane Sinks in Upland Soils Under Future Climate Change.Global change biology · 2026Article
- An integrated global resource of wetland microbiomes linking environmental metadata, community profiles, and genome-resolved metabolic traits.Scientific data · 2026Article
- Article
- Leveraging AI and integrated genomic-enviromic prediction for intelligent sugarcane breeding.Plant communications · 2026Review
- Metabolic inequality in microbial communities.bioRxiv : the preprint server for biology · 2026Article
- 16S rRNA sequence captures microbial functional potential.bioRxiv : the preprint server for biology · 2026Article
- Depth of nutrient uptake by deep-rooted plants is regulated by water availability.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Climate change leads to significant loss of soil inorganic carbon.National science review · 2026Article
- Nutrient limitation shapes functional traits of mycorrhizal fungi and phosphorus-cycling bacteria across an elevation gradient.mSystems · 2026Article
- From microbial diversity to functional potential using dimensionality reduction.Frontiers in microbiology · 2026Article
- Ultra-deep long-read metagenomics captures diverse taxonomic and biosynthetic potential of soil microbes.GigaScience · 2025Article
- The interplay of carbon and nitrogen cycling driven by watershed microorganisms.Frontiers in microbiology · 2025Review
- Deciphering microbial spatial organization: insights from synthetic and engineered communities.ISME communications · 2025Review
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
Microbes drive the biogeochemical cycles of earth systems, yet the long-standing goal of linking emerging genomic information, microbial traits, mechanistic ecosystem models, and projections under climate change has remained elusive despite a wealth of emerging genomic information. Here we developed a general genome-to-ecosystem (G2E) framework for integrating genome-inferred microbial kinetic traits into mechanistic models of terrestrial ecosystems and applied it at a well-studied Arctic wetland by benchmarking predictions against observed greenhouse gas emissions. We found variation in genome-inferred microbial kinetic traits resulted in large differences in simulated annual methane emissions, quantitatively demonstrating that the genomically observable variations in microbial capacity are consequential for ecosystem functioning. Applying microbial community-aggregated traits via genome relative-abundance-weighting gave better methane emissions predictions (i.e., up to 54% decrease in bias) compared to ignoring the observed abundances, highlighting the value of combined trait inferences and abundances. This work provides an example of integrating microbial functional trait-based genomics, mechanistic and pragmatic trait parameterizations of diverse microbial metabolisms, and mechanistic ecosystem modeling. The generalizable G2E framework will enable the use of abundant microbial metagenomics data to improve predictions of microbial interactions in many complex systems, including oceanic microbiomes.
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Registered trials
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