ArticleNature communications2025
Janus hydrogel microrobots with bioactive ions for the regeneration of tendon-bone interface.
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Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
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Who cites it
22 citing papers in PubMed.
- Antifibrotic hydrogel strategies for scarless tissue regeneration: mechanisms, design, and application.Bioactive materials · 2027Review
- Single-cell transcriptome-guided biomimetic magnetothermal hydrogel microspheres for multimodal eradication of residual glioblastoma.Bioactive materials · 2026Article
- A Collagen-based Scaffold Supports Tendon-to-bone Healing After Rotator Cuff Repair: An Integrated Translational Study.Advanced healthcare materials · 2026Article
- Liposomal multimodal theranostics for bone disorders: from rational responsive delivery and biomimetic strategies to clinical translation.Journal of nanobiotechnology · 2026Review
- Biomimetic double-layered electrospun nanofibrous scaffold with mussel adhesive protein coating and TGF-β3 encapsulation for enhanced tendon-bone healing in rotator cuff tears.Materials today. Bio · 2026Article
- Biophysical signal-driven scaffold design for stem cell-guided osteochondral regeneration.Bioactive materials · 2026Review
- Hydrogel-Based Micro/Nanorobots for Advanced Biomedical Applications.Gels (Basel, Switzerland) · 2026Review
- Modular assembly of nanocomposite hydrogel with NIR-responsive black phosphorus release and mild photothermal synergy for enhanced regenerative microenvironment and accelerated infectious bone repair.Journal of nanobiotechnology · 2026Article
- Innovative applications of multidimensional engineered hydrogels in wound healing.Journal of advanced research · 2026Review
- Highly bio-adapted hydrogels for tendon-bone interface regeneration: Natural healing inspiration, design strategies, and biomedical potential.Bioactive materials · 2026Review
- A decoupling strategy toward spatiotemporal regulation and biomechanical transmission of sandwiched scaffold for osteochondral regeneration.Nature communications · 2026Article
- VEGF-sustained regulation and hydrogel-activated graded porous titanium scaffold for functional regeneration of the tendon-bone interface.Materials today. Bio · 2026Article
- Microgel-Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From physical modalities to energy-responsive biomaterials: Current strategies and challenges in tendon-to-bone healing.Bioactive materials · 2026Review
- Engineered bacterial therapy suppresses Enterohemorrhagic Escherichia coli through metabolic competition and virulence silencing.Nature communications · 2026Article
- Continuous fabrication of Janus liquid crystal elastomer fibers with programmable actuation.Nature communications · 2026Article
- Hydrogel Microspheres for Biomedical Applications.Small science · 2026Review
- Mitochondrial transfer and transplantation in tendon, ligament, and enthesis repair: current evidence, mechanistic rationale, and regenerative opportunities.Frontiers in cell and developmental biology · 2026Review
- Janus Microgel Robots for Actively Boosting Catalytic Efficiency and Recovery of Living Materials.Research (Washington, D.C.) · 2026Article
- NIR-II Responsive Multifunctional Scaffold Enabling "Kill-Modulation-Build" Synergistic Therapy for Infectious Bone Defects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
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Authors and funding
15 authors.
Zichuan Ding *Orthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
Yongrui Cai *Orthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
Haocheng SunOrthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
Xiao RongDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.ORCID http://orcid.org/0000-0002-3780-3902
Sipei YeCAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technology of China, Hefei, China.
Jiaxuan FanOrthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
Yahao LaiOrthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
Zhimin LiangWest China School of Nursing, Sichuan University, Chengdu, China.
Chao HuangOrthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
Peilin LiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu, China.ORCID http://orcid.org/0000-0001-9030-4347
Xiaoxue FuOrthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
Liu WangCAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technology of China, Hefei, China.ORCID http://orcid.org/0000-0001-7014-9976
Guosheng TangGuangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, the Fifth Affiliated Hospital and School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China. guoshengtang@gzhmu.edu.cn.ORCID http://orcid.org/0009-0009-2791-8448
Zongke ZhouOrthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China. zhouzongke@scu.edu.cn.ORCID http://orcid.org/0000-0002-9037-4756
Zeyu LuoOrthopaedic Research Institute, Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China. luozy@wchscu.edu.cn.ORCID http://orcid.org/0009-0003-3890-0784
Funding
China Postdoctoral Science Foundation 2023M742478Department of Science and Technology of Sichuan Province (Sichuan Provincial Department of Science and Technology) 2023YFH0068National Natural Science Foundation of China (National Science Foundation of China) 82172394National Natural Science Foundation of China (National Science Foundation of China) 82302786
Abstract
Regenerating natural gradients of the tendon‒bone interface (TBI) is a major challenge in the reconstruction of rotator cuff tear (RCT). In this study, magnetic Janus hydrogel microrobots to match the TBI orientation during RCT reconstruction surgery are developed via a biofriendly gas-shearing microfluidic platform. Through separate loading of Mg
Indexed as
Bone and BonesHydrogelsRegenerationRotator Cuff InjuriesTendonsAnimalsIonsMagnesiumMaleRatsRats, Sprague-DawleyRoboticsZincHydrogelsIonsMagnesiumZinc
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.