ArticleJournal of general internal medicine2026
Current and Future Cost Burden of Myocardial Infarction in Australia: Dynamic Multistate Markov Model.
Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
introductionMyocardial infarction (MI) imposes a significant health burden to the Australian population. However, detailed economic implication of MI on the Australian healthcare system has not been exhaustively explored.
objectiveTo estimate the current chronic management cost and project the future healthcare cost burden of MI, from the Australian healthcare system perspective.
designA generalized linear model with a gamma outcome distribution and negative inverse link function was used to estimate the current chronic management cost burden of MI while a dynamic multistate Markov model constructed to project the future healthcare cost burden of MI over 20 years (2019-2038). For all projected costs, 5% annual discounting was applied in the base case, as per Australian guidelines.
participantsWe identified all people, 59,260, aged ≥ 30 years discharged from a public or private hospital following MI between 2012 and 2017 from the Victorian Admitted Episode Dataset. We estimated annual chronic management cost of MI by age, sex, socioeconomic disadvantage and years of follow-up. We used these data to project the future healthcare cost burden of MI. MAIN MEASURE: Cost in Australian dollar (AUD). KEY
resultsThe current annual chronic management cost of MI was estimated to be AUD 14,412 (95% confidence interval: AUD 14,282, AUD 14,542) per person. This cost was higher among advanced age group, male participants, during first year of follow-up and people in the most socioeconomically disadvantaged quintile. The projected total healthcare cost following MI was AUD 85.1 billion (95% uncertainty interval AUD 80.8 billion, AUD 89.8 billion) from 2019 to 2038.
conclusionOur projections suggest that MI will cost the Australian healthcare system over AUD 85 billion in the coming years. Cost estimates based on key sociodemographic characteristics and socioeconomic disadvantage are expected to inform future health economic modelling studies for MI prevention strategies and interventions.
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