Evidence map›Paper›PMID 40038130›Full record

Observational studyArchives of gynecology and obstetrics2025

Hysteroscopic niche resection can effectively reduce the niche volume, increase residual myometrial thickness, and improve postmenstrual spotting symptoms.

Yang Wang, Wei Xia, Taotao Sun, Lirong Yan, Chuqing He, Judith A F Huirne, Jian Zhang

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yang WangDepartment of Gynecology and Obstetrics, International Peace Maternity and Child, Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wei XiaDepartment of Gynecology and Obstetrics, International Peace Maternity and Child, Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Taotao SunShanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.
Lirong YanDepartment of Gynecology and Obstetrics, International Peace Maternity and Child, Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chuqing HeDepartment of Gynecology and Obstetrics, International Peace Maternity and Child, Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Judith A F Huirne *Department of Obstetrics and Gynaecology, Amsterdam Reproduction and Development Research Institute, Amsterdam University Medical Centers, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
Jian Zhang *Department of Gynecology and Obstetrics, International Peace Maternity and Child, Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhangjian_ipmch@sjtu.edu.cn.

Funding

Clinical Research Project of Shanghai Jiao Tong University YG2021ZD31, YG2023QNB27, YG2024QNA58, YG2024QNA57, YG2025QNA12Medical Innovation Research Project of Shanghai Science and Technology Commission 23Y11909100
6 · The paper itself

Abstract

purposeTo compare the anatomical changes of the uterine niche in women before and after hysteroscopic niche resection (HNR) and to investigate the correlation between these changes and the improvement in postoperative spotting symptoms by thin-slice MRI.

methodsThis prospective observational study enrolled women with symptomatic uterine niches between June 2019 and February 2024. All participants underwent thin-slice magnetic resonance imaging (MRI) before and after HNR. We assessed the effective rate of postoperative spotting at the 6-month follow-up (effective treatment was defined as a reduction of at least 50% in spotting days relative to baseline during the 6-month follow-up period) and the pre- and post-HNR anatomical indicators.

resultsA total of 108 women were included in the study. Six months after HNR, 70.4% (76/108) of women experienced at least a 50% reduction in spotting days from baseline. Residual myometrial thickness (RMT) significantly increased by 1.9 ± 2.2 mm (p < 0.01). The volume of niche significantly decreased, with a median reduction rate of 38.5% (IQR 8.5-88.2%) (p < 0.01). Based on the ROC curve, a cut-off value of 50 mm

conclusionHNR is a promising approach for managing postmenstrual spotting, especially in treating small uterine niches (volume < 50 mm

Indexed as

HysteroscopyMetrorrhagiaMyometriumUterusAdultFemaleHumansMagnetic Resonance ImagingMiddle AgedProspective StudiesTreatment OutcomeAnatomical structureHysteroscopic resectionPostmenstrual spottingThin-slice MRIUterine niche

Identifiers

PMID40038130
PMCPMC12176920

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.