Evidence map›Paper›PMID 40037947›Full record

ArticleBritish journal of anaesthesia2025

Automated structured data extraction from intraoperative echocardiography reports using large language models.

Emily J MacKay, Shir Goldfinger, Trevor J Chan, Rachel H Grasfield, Vikram J Eswar, Kelly Li, Quy Cao, Alison M Pouch

Abstract read
In one paragraph

Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

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0cells of the map it votes in
10citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  10. Generative AI models: the next anaesthetic agent?British journal of anaesthesia · 2025
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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Emily J MacKayDepartment of Anaesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Penn Center for Perioperative Outcomes Research and Transformation (CPORT), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Penn's Cardiovascular Outcomes, Quality and Evaluative Research Center (CAVOQER), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: emily.mackay@pennmedicine.upenn.edu.
Shir GoldfingerDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.
Trevor J ChanDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Rachel H GrasfieldSchool of Medicine and Health Sciences, Des Moines University, Des Moines, IA, USA.
Vikram J EswarDepartment of Anaesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kelly LiHarvard Medical School, Harvard University, Boston, MA, USA.
Quy CaoDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Alison M PouchDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.

Funding

4D Multimodal Image-Based Modeling for Bicuspid Aortic Valve Repair SurgeryR01HL163202 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Alison Marie Pouch · 2022 to 2026
$3.5M
The Role of Intraoperative Transesophageal Echocardiography During Isolated Coronary Artery Bypass Graft SurgeryK23HL166964 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Emily Jane Mackay · 2023 to 2026
$731k
NHLBI NIH HHS K23 HL166964NHLBI NIH HHS R01 HL163202
6 · The paper itself

Abstract

backgroundConsensus-based large language model (LLM) ensembles might provide an automated solution for extracting structured data from unstructured text in echocardiography reports.

methodsThis cross-sectional study utilised 600 intraoperative transoesophageal reports (100 for prompt engineering; 500 for testing) randomly sampled from 7106 adult patients undergoing cardiac surgery at two hospitals within the University of Pennsylvania Healthcare System. Three echocardiographic parameters (left ventricular ejection fraction, right ventricular systolic function, and tricuspid regurgitation) were extracted from both the presurgical and postsurgical sections of the reports. LLM ensembles were generated using five open-source LLMs and four voting strategies: (1) unanimous (five out of five in agreement); (2) supermajority (four or more of five in agreement); (3) majority (three or more of five in agreement); and (4) plurality (two or more of five in agreement). Returned LLM ensemble responses were compared with the reference standard dataset to calculate raw accuracy, consensus accuracy, error rate, and yield.

resultsOf the four LLM ensembles, the unanimous LLM ensemble achieved the highest consensus accuracies (99.4% presurgical; 97.9% postsurgical) and the lowest error rates (0.6% presurgical; 2.1% postsurgical) but had the lowest data extraction yields (81.7% presurgical; 80.5% postsurgical) and the lowest raw accuracies (81.2% presurgical; 78.9% postsurgical). In contrast, the plurality LLM ensemble achieved the highest raw accuracies (96.1% presurgical; 93.7% postsurgical) and the highest data extraction yields (99.4% presurgical; 98.9% postsurgical) but had the lowest consensus accuracies (96.7% presurgical; 94.7% postsurgical) and highest error rates (3.3% presurgical; 5.3% postsurgical).

conclusionsA consensus-based LLM ensemble successfully generated structured data from unstructured text contained in intraoperative transoesophageal reports.

Indexed as

EchocardiographyEchocardiography, TransesophagealInformation Storage and RetrievalMonitoring, IntraoperativeNatural Language ProcessingAdultAgedCardiac Surgical ProceduresCross-Sectional StudiesFemaleHumansLarge Language ModelsMaleMiddle Agedartificial intelligence (AI)cardiac surgeryechocardiographylarge language modelsperioperative medicine

Identifiers

PMID40037947
PMCPMC12106877

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.