ArticleSchizophrenia bulletin2025
The Relationship Among Range Adaptation, Social Anhedonia, and Social Functioning: A Combined Magnetic Resonance Spectroscopy and Resting-State fMRI Study.
Article in Schizophrenia bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Abnormal resting-state functional connectivity in anhedonia: A systematic review and meta-analysis.Brain imaging and behavior · 2026Pooled it
- Theory of mind difficulties in people with social anhedonia: Evidence from behavioural and task-based functional magnetic resonance imaging findings.Schizophrenia research. Cognition · 2026Article
- Anhedonia Across and Beyond the Schizophrenia Spectrum.Schizophrenia bulletin · 2025Review
- Neuroscience of Schizotypy: A Translational Perspective From Phenotype to Genetics and Brain Networks.Schizophrenia bulletin · 2025Article
- Neuropsychology and Neurobiology of Negative Schizotypy: A Selective Review.Biological psychiatry global open science · 2024Review
- Range adaptation in schizophrenia: A one-year longitudinal study.Schizophrenia research. Cognition · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
background and hypothesisSocial anhedonia is a core feature of schizotypy and correlates significantly with social functioning and range adaptation. Range adaptation refers to representing a stimulus value based on its relative position in the range of pre-experienced values. This study aimed to examine the resting-state neural correlates of range adaptation and its associations with social anhedonia and social functioning. STUDY
designIn study 1, 60 participants completed resting-state magnetic resonance spectroscopy and fMRI scans. Range adaptation was assessed by a valid effort-based decision-making paradigm. Self-reported questionnaires was used to measure social anhedonia and social functioning. Study 2 utilized 26 pairs of participants with high (HSoA) and low levels of social anhedonia (LSoA) to examine the group difference in range adaptation's neural correlates and its relationship with social anhedonia and social functioning. An independent sample of 40 pairs of HSoA and LSoA was used to verify the findings. STUDY
resultsStudy 1 showed that range adaptation correlated with excitation-inhibition balance (EIB) and ventral prefrontal cortex (vPFC) functional connectivity, which in turn correlating positively with social functioning. Range adaptation was specifically determined by the EIB via mediation of ventral-medial prefrontal cortex functional connectivities. Study 2 found HSoA and LSoA participants exhibiting comparable EIB and vPFC connectivities. However, EIB and vPFC connectivities were negatively correlated with social anhedonia and social functioning in HSoA participants.
conclusionsEIB and vPFC functional connectivity is putative neural correlates for range adaptation. Such neural correlates are associated with social anhedonia and social functioning.
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