Evidence map›Paper›PMID 40037619›Full record

ArticleThe oncologist2025

Resource utilization and inpatient hospitalization costs associated with thromboembolic events among patients with polycythemia vera.

Jingbo Yu, Julie Gayle, Ning Rosenthal, Harold Brown, Evan Braunstein, Naveen Pemmaraju

Abstract read
In one paragraph

Article in The oncologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingbo YuIncyte Corporation, Health Economics and Outcomes, Wilmington, DE 19803, United States.ORCID 0000-0001-9819-0735
Julie GaylePINC AI™ Applied Sciences, Premier Inc., Charlotte, NC 28277, United States.
Ning RosenthalPINC AI™ Applied Sciences, Premier Inc., Charlotte, NC 28277, United States.
Harold BrownPINC AI™ Applied Sciences, Premier Inc., Charlotte, NC 28277, United States.ORCID 0009-0005-7993-5451
Evan BraunsteinIncyte Corporation, Health Economics and Outcomes, Wilmington, DE 19803, United States.
Naveen PemmarajuDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.

Funding

Incyte Corporation
6 · The paper itself

Abstract

backgroundHealthcare resource utilization (HCRU) and costs are often elevated in patients with polycythemia vera (PV), and this patient population has an increased risk of developing thromboembolic events (TEs). This study describes HCRU, costs, and mortality during TE-related hospitalizations among patients with PV in a contemporary real-world setting in the United States. PATIENTS AND

methodsThis retrospective cohort study included adult inpatients with PV and TE discharged from 623 hospitals between January 1, 2017, and June 30, 2020 with a 2-year follow-up period after the first TE-related (index) hospitalization. Data were abstracted from the PINC AI Healthcare database, which includes 25% of US inpatient discharges.

resultsAmong 3494 patients (index TE: arterial, 69.1%; venous, 27.1%; both, 3.7%), mean (SD) age was 70.7 (14) years, and most patients were male (58.6%), White (81.2%), with Medicare insurance (72.6%). Mean (SD) Charlson Comorbidity Index score was 3.2 (2.3). Mean total hospitalization costs were $24 403 during the index hospitalization (mean [SD] hospital length of stay [LOS], 7 [9] days). A third (n = 1150) of patients were admitted to the intensive care unit (mean cost, $29 342; mean [SD] LOS, 5 [7] days). During 30 days and 2 years of follow-up, the TE-related readmission rate was 6.4% and 20.0%, respectively. All-cause mortality was 6.2% during index hospitalization; an additional 4.7% occurred during the 2-year follow-up period.

conclusionAmong patients with PV and TE, inpatient hospitalization HCRU, costs, and mortality were substantial. These findings highlight the importance of preventing TEs in the management of PV.

Indexed as

Health ResourcesHospitalizationPolycythemia VeraThromboembolismAdultAgedAged, 80 and overFemaleHumansInpatientsMaleMiddle AgedRetrospective StudiesUnited Statescostembolismhospitalinpatientpolycythemia verathrombosis

Identifiers

PMID40037619
PMCPMC11879438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.