Evidence map›Paper›PMID 40037610›Full record

ArticleInternational journal for quality in health care : journal of the International Society for Quality in Health Care2025

Look-alike, sound-alike medication perioperative incidents in a regional Australian hospital: assessment using a novel medication safety culture assessment tool.

Alexandra N Ryan, Kelvin L Robertson, Beverley D Glass

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Article in International journal for quality in health care : journal of the International Society for Quality in Health Care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Alexandra N RyanPharmacy Department, Townsville University Hospital, 100 Angus Smith Drive, Douglas, Queensland 4814, Australia.ORCID 0000-0002-3098-1036
Kelvin L RobertsonPharmacy Department, Townsville University Hospital, 100 Angus Smith Drive, Douglas, Queensland 4814, Australia.ORCID 0000-0001-8411-1864
Beverley D GlassCollege of Medicine & Dentistry, James Cook University, 1 James Cook Drive, Douglas, Queensland 4811, Australia.ORCID 0000-0002-5444-3312

Funding

Townsville Hospital & Health Service, Study Education and Research Trust Account (SERTA) Fund Fellowship Grant [2022_RFG3]
6 · The paper itself

Abstract

backgroundMedication safety remains a global concern, with governments and organizations striving to mitigate preventable patient harm across healthcare systems. Look-alike, sound-alike medication incidents and the safety culture are widely acknowledged as a contributor to medication errors, particularly within the high-risk perioperative environment. The Medication Safety Culture Indicator Matrix (MedSCIM) is a novel tool developed by the Canadian Institute for Safe Medication Practices to assess the maturity of the medication safety culture. This study aims to delineate look-alike sound-alike (LASA) medication incidents reported in the pharmacy and perioperative settings of an Australian hospital and assess the maturity of the medication safety culture.

methodsThe study setting is within a large regional hospital in Australia, servicing both adult and paediatric populations. Medication incidents from 1 April 2018 to 1 April 2023 were retrospectively gathered from the Clinical Incident Management System, Riskman®. Data and statistical analyses were carried out using Microsoft Excel®. The necessary approvals were secured from the Heath Service Human Research and Ethics Committee.

resultsDuring the 5-year period, a total of 246 (4.1%) of the 6002 medication incidents within the health service were identified as meeting the inclusion criteria. Of the 246 medication incidents, 63.0% were identified from the Pharmacy Department, while 22.0% and 15.0% were from the Post Anaesthetic Care Unit and Anaesthetics Department, respectively. The most frequently reported incident classification in both the Anaesthetics Department and Post Anaesthetic Care Unit was 'incorrect dose', followed by 'incorrect medication'. Throughout the 5-year period, 46 (18.7%) of the 246 medication incidents were attributed to look-alike, sound-alike sources of error, predominantly identified in the Pharmacy Department (73.9%), followed by the Anaesthetics Department (17.4%) and the Post Anaesthetic Care Unit (8.7%). High-risk medications were most frequently reported to the Anaesthetics Department. Packaging (packaging alone, naming and packaging, and syringe swaps) was determined to be a contributing factor in 30 (65.2%) of the 46 LASA medication incidents. MedSCIM assessment revealed a reactive medication safety culture. Additionally, the medication incident report documentation was found to be mostly complete or semi-complete.

conclusionOur analysis delineated medication incidents occurring across the entire medication management cycle and identified incidents related to LASA medications as a contributor to medication incidents across these clinical settings. This novel medication safety culture tool assessment highlighted opportunities for improvement with clinical incident documentation.

Indexed as

Medication ErrorsPatient SafetySafety ManagementAdultAustraliaHumansRetrospective Studieshospitallook-alikemedication incidentsmedication safety cultureperioperativepharmacysound-alike (LASA)

Identifiers

PMID40037610
PMCPMC11934547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.